Targeting PI3K in cancer: mechanisms and advances in clinical trials
Abstract Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR)
signaling is one of the most important intracellular pathways, which can be considered as a …
signaling is one of the most important intracellular pathways, which can be considered as a …
PI3K inhibitors in cancer: clinical implications and adverse effects
The phospatidylinositol-3 kinase (PI3K) pathway is a crucial intracellular signaling pathway
which is mutated or amplified in a wide variety of cancers including breast, gastric, ovarian …
which is mutated or amplified in a wide variety of cancers including breast, gastric, ovarian …
New insights into long noncoding RNAs and their roles in glioma
Z Peng, C Liu, M Wu - Molecular cancer, 2018 - Springer
Glioma is one of the most prevalent types of primary intracranial carcinoma with varying
malignancy grades I–IV and histological subtypes, including astrocytomas, glioblastoma …
malignancy grades I–IV and histological subtypes, including astrocytomas, glioblastoma …
Long noncoding RNAs as biomarkers in cancer
L Bolha, M Ravnik-Glavač, D Glavač - Disease markers, 2017 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …
Interaction and cross-talk between non-coding RNAs
S Yamamura, M Imai-Sumida, Y Tanaka… - Cellular and molecular …, 2018 - Springer
Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and
functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a …
functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a …
Long non‐coding RNA s as an epigenetic regulator in human cancers
Y Kondo, K Shinjo, K Katsushima - Cancer science, 2017 - Wiley Online Library
Recent studies have described the important multiple roles of long non‐coding RNA s (lnc
RNA s) during oncogenic transformation. Because the coding genome accounts for a small …
RNA s) during oncogenic transformation. Because the coding genome accounts for a small …
[HTML][HTML] Upregulated lncRNA SNHG1 contributes to progression of non-small cell lung cancer through inhibition of miR-101-3p and activation of Wnt/β-catenin …
Y Cui, F Zhang, C Zhu, L Geng, T Tian, H Liu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Lung cancer is the most common and aggressive tumor in the world. Long non-coding RNA
small nucleolar RNA host gene 1 (lncRNA SNHG1) play critical roles in the progression of …
small nucleolar RNA host gene 1 (lncRNA SNHG1) play critical roles in the progression of …
Crosstalk between long noncoding RNAs and microRNAs in health and disease
AS Bayoumi, A Sayed, Z Broskova, JP Teoh… - International journal of …, 2016 - mdpi.com
Protein-coding genes account for only a small part of the human genome; in fact, the vast
majority of transcripts are comprised of non-coding RNAs (ncRNAs) including long ncRNAs …
majority of transcripts are comprised of non-coding RNAs (ncRNAs) including long ncRNAs …
Retracted: CRNDE promotes malignant progression of glioma by attenuating miR-384/PIWIL4/STAT3 Axis
J Zheng, X Liu, P Wang, Y Xue, J Ma, C Qu, Y Liu - Molecular therapy, 2016 - cell.com
Colorectal neoplasia differentially expressed (CRNDE) is the most upregulated long
noncoding RNA (lncRNA) in glioma. Herein, the function and potential molecular …
noncoding RNA (lncRNA) in glioma. Herein, the function and potential molecular …
Functional interaction among lncRNA HOTAIR and microRNAs in cancer and other human diseases
M Cantile, M Di Bonito, M Tracey De Bellis, G Botti - Cancers, 2021 - mdpi.com
Simple Summary This review aimed to describe the contribution of functional interaction
between the lncRNA HOTAIR and microRNAs in human diseases, including cancer …
between the lncRNA HOTAIR and microRNAs in human diseases, including cancer …