Boron neutron capture therapy (BNCT) is a selective biological targeted nuclide technique
for cancer therapy. It has the following attractive features: good targeting, high effectiveness …

After uptake by U87 MG and A375 cancer cells, cobaltabisdicarbollide [COSAN]− distributes
between membrane and nucleus and presents no relevant cytotoxicity against both cell lines …

Since Locher proposed the concept of boron neutron capture therapy (BNCT) in 1936, it has
become a great challenge in the field of medicinal chemistry. The great dare has been to …

The efficacy of boron neutron capture therapy depends on the selective delivery of 10 B to
the target. Integrins αvβ3 are transmembrane receptors over-expressed in both glioblastoma …

Anticancer drugs inhibit DNA replication by intercalating between DNA base pairs, forming
covalent bonds with nucleotide bases, or binding to the DNA groove. To develop safer …

In this study, we have synthesized and characterized a pure boron nanoparticle containing
asolectin phospholipid-based liposome construct prepared using a water-in-oil emulsion …

The reported new anilinoquinazoline‐icosahedral borane hybrids have been evaluated as
glioma targeting for potential use in cancer therapy. Their anti‐glioma activity depends on …

For the first time, the direct C (sp2)–H functionalization methodology has successfully been
applied to cause nucleophilic modification of mono-and diazine-N-oxides with the 1, 2-closo …

The direct C–H functionalization methodology has first been applied to perform transition
metal-free C–H/C–Li cross-couplings of 2H-imidazole 1-oxides with carboranyllithium. This …

The uptake of (10) boron by tumor cells plays an important role for cell damage in boron
neutron capture therapy (BNCT). CD133 is frequently expressed in the membrane of glioma …