The natural history of cervical HPV infection: unresolved issues

CBJ Woodman, SI Collins, LS Young - Nature Reviews Cancer, 2007 - nature.com
The identification of high-risk human papillomavirus (HPV) types as a necessary cause of
cervical cancer offers the prospect of effective primary prevention and the possibility of …

Integration of high‐risk human papillomavirus: a key event in cervical carcinogenesis?

M Pett, N Coleman - The Journal of Pathology: A Journal of the …, 2007 - Wiley Online Library
An important occurrence in cervical carcinogenesis is deregulated expression of the high‐
risk human papillomavirus (HR‐HPV) oncogenes E6 and E7. Several risk factors for cervical …

Organization of human papillomavirus productive cycle during neoplastic progression provides a basis for selection of diagnostic markers

K Middleton, W Peh, S Southern, H Griffin… - Journal of …, 2003 - Am Soc Microbiol
The productive cycle of human papillomaviruses (HPVs) can be divided into discrete
phases. Cell proliferation and episomal maintenance in the lower epithelial layers are …

Human papillomavirus type 16 integration in cervical carcinoma in situ and in invasive cervical cancer

H Arias-Pulido, CL Peyton, NE Joste… - Journal of clinical …, 2006 - Am Soc Microbiol
Integration of human papillomavirus type 16 (HPV-16) into the host DNA has been proposed
as a potential marker of cervical neoplastic progression. In this study, a quantitative real-time …

HPV integration begins in the tonsillar crypt and leads to the alteration of p16, EGFR and c‐myc during tumor formation

SH Kim, BS Koo, S Kang, K Park, H Kim… - … journal of cancer, 2007 - Wiley Online Library
The prevalence of human papillomavirus (HPV) infection is high in the oropharyngeal
mucosal regions, of which the tonsil is the most commonly affected. There may be a link …

Molecular mechanisms of HPV mediated neoplastic progression

R Senapati, NN Senapati, B Dwibedi - Infectious Agents and Cancer, 2016 - Springer
Human Papillomavirus is the major etiological agent in the development of cervical cancer
but not a sufficient cause. Despite significant research, the underlying mechanisms of …

Selection of cervical keratinocytes containing integrated HPV16 associates with episome loss and an endogenous antiviral response

MR Pett, MT Herdman, RD Palmer… - Proceedings of the …, 2006 - National Acad Sciences
Integration of high-risk human papillomavirus (HRHPV) into the host genome is a key event
in cervical neoplastic progression. Integration is associated with deregulated expression of …

Could human papillomaviruses be spread through blood?

S Bodaghi, LV Wood, G Roby, C Ryder… - Journal of clinical …, 2005 - Am Soc Microbiol
The human papillomaviruses (HPVs) are epitheliotropic viruses that require the environment
of a differentiating squamous epithelium for their life cycle. HPV infection through abrasion of …

Viral DNA load, physical status and E2/E6 ratio as markers to grade HPV16 positive women for high-grade cervical lesions

M Cricca, AM Morselli-Labate, S Venturoli… - Gynecologic …, 2007 - Elsevier
OBJECTIVES.: Cervical intraepithelial neoplasias (CIN) associated with high-risk (HR)
human papillomavirus infection, in addition to HR-HPV typing need other viral marker testing …

Analysis of human papillomavirus type 16 (HPV16) DNA load and physical state for identification of HPV16-infected women with high-grade lesions or cervical …

M Saunier, S Monnier-Benoit, F Mauny… - Journal of clinical …, 2008 - Am Soc Microbiol
Integration of human papillomavirus (HPV) DNA into the host cell genome is a frequent
event in cervical carcinogenesis, even though this phenomenon does not seem to be …