Excipients are generally pharmacologically inert, but can interact with drugs in the dosage
form and the physiological factors at the site of absorption to affect the bioavailability of a …

Minerals are widely used in the pharmaceutical industry as lubricants, desiccants,
disintegrants, diluents, binders, pigments and opacifiers, as well as emulsifying, thickening …

One may consider that drug-drug interactions (DDIs) associated with antacids is an obsolete
topic because they are prescribed less frequently by medical professionals due to the …

Представлены результаты сравнительного исследования, включившего 16
добровольцев, в котором оценивали всасывание различных форм (раствора для питья …

Objectives Drug-excipient binding can affect in-vitro drug release. Literature suggests that
drug-excipient ionic binding interaction that is not disrupted by physiological salt …

A highly water-soluble antihypertensive drug, metoprolol tartrate (MT), was selected as a
model drug for preparation of multi-walled carbon nanotubes (MWCNTs)-impregnated ethyl …

Сульфат магния использовался в аллопатической медицине более 300 лет как
слабительное. В XX веке отметилось значительное расширение спектра клинических …

Unintended physicochemical interaction of an excipient with a drug substance in a dosage
form can result in the complexation or binding of the drug, resulting in slow and/or …

Objective To study the effect of the concomitant consumption of kolanut, a caffeine-
containing nut, on the pharmacokinetics of halofantrine. Methods A single dose of 500 mg …

Aims To investigate the effect of tetracycline co‐administration on the pharmacokinetics of
halofantrine in healthy subjects. Methods Eight healthy males were each given 500 mg …