Glial calcium: homeostasis and signaling function

A Verkhratsky, RK Orkand… - Physiological …, 1998 - journals.physiology.org
Verkhratsky, Alexej, Richard K. Orkand, and Helmut Kettenmann. Glial Calcium:
Homeostasis and Signaling Function. Physiol. Rev. 78: 99–141, 1998.—Glial cells respond …

The endothelin system and its potential as a therapeutic target in cardiovascular disease

GA Gray, DJ Webb - Pharmacology & therapeutics, 1996 - Elsevier
Endothelin (ET)-1, an endothelium-derived peptide, is the most potent vasoconstrictor agent
described to date. ET-1 also has positive inotropic and chronotropic effects in the heart and …

[图书][B] Brenner & Rector's the kidney

K Skorecki, GM Chertow, PA Marsden, MW Taal… - 2016 - doctorlib.info
The volume of extracellular fluid (ECF) is maintained within narrow limits in normal human
subjects, despite day-to-day variations in dietary intake of salt and water over a wide range …

Endothelin-converting Enzyme-2 Is a Membrane-bound, Phosphoramidon-sensitive Metalloprotease with Acidic pH Optimum (∗)

N Emoto, M Yanagisawa - Journal of Biological Chemistry, 1995 - ASBMB
Endothelins (ET) are a family of potent vasoactive peptides that are produced from
biologically inactive intermediates, termed big endothelins, via a proteolytic processing at …

Endothelin adrenocortical secretagogue effect is mediated by the B receptor in rats

AS Belloni, GP Rossi, PG Andreis, G Neri, G Albertin… - …, 1996 - Am Heart Assoc
We investigated the gene expression and localization of endothelin-1 (ET-1) receptor
subtypes ETA and ETB in the rat adrenal cortex as well as their involvement in the …

Ambrisentan, a non‐peptide endothelin receptor antagonist

H Vatter, V Seifert - Cardiovascular drug reviews, 2006 - Wiley Online Library
Increasing numbers of experimental investigations and recently also of clinical trials strongly
suggest an integral involvement of the endothelin (ET)‐system in the pathophysiology of a …

Presence of contractile endothelin-A and dilatory endothelin-B receptors in human cerebral arteries

T Nilsson, L Cantera, M Adner, L Edvinsson - Neurosurgery, 1997 - journals.lww.com
OBJECTIVE: The aim of the present study was to elucidate the endothelin receptor subtypes
responsible for the endothelin-induced vasomotor responses of human cerebral arteries …

Autocrine-paracrine endothelin system in the physiology and pathology of steroid-secreting tissues

GG Nussdorfer, GP Rossi, LK Malendowicz… - Pharmacological …, 1999 - ASPET
Endothelins (ETs) 2 are a family of endogenous peptides, mainly secreted by endothelial
cells, which exert a potent vasoconstrictor and pressor activity, acting through two classes of …

Endothelin-1 Binding to Endothelin Receptors in the Rat Anterior Pituitary Gland: Possible Formation of an ETA–ETB Receptor Heterodimer

N Harada, A Himeno, K Shigematsu… - Cellular and molecular …, 2002 - Springer
Interaction in the recognition of endothelin-1 (ET-1), a typical bivalent ET receptor-ligand,
between ET A and ET B receptors was investigated in the rat anterior pituitary gland, using …

Endothelin receptor antagonism

TJ Opgenorth - Advances in pharmacology, 1995 - Elsevier
Publisher Summary The intent of the present chapter is to emphasize information about the
pharmacology of endothelin (ET) receptor antagonists and work relating to investigations …