[HTML][HTML] Cancer-associated muscle weakness-From triggers to molecular mechanisms
Skeletal muscle weakness is a debilitating consequence of many malignancies. Muscle
weakness has a negative impact on both patient wellbeing and outcome in a range of …
weakness has a negative impact on both patient wellbeing and outcome in a range of …
Myogenic microRNAs as Therapeutic Targets for Skeletal Muscle Mass Wasting in Breast Cancer Models
M Artigas-Arias, R Curi, GN Marzuca-Nassr - International Journal of …, 2024 - mdpi.com
Breast cancer is the type of cancer with the highest prevalence in women worldwide.
Skeletal muscle atrophy is an important prognostic factor in women diagnosed with breast …
Skeletal muscle atrophy is an important prognostic factor in women diagnosed with breast …
The miR-6240 target gene Igf2bp3 promotes myoblast fusion by enhancing myomaker mRNA stability
Y Huang, W Wang, X Fan, X Liu, W Liu, Z Wang… - Cellular & Molecular …, 2024 - Springer
Myoblast fusion plays a crucial role in myogenesis. Insulin-like growth factor 2 mRNA-
binding protein 3 (IGF2BP3) functions as an RNA N6-methyladenosine reader and exerts …
binding protein 3 (IGF2BP3) functions as an RNA N6-methyladenosine reader and exerts …
Muscle-enriched microRNA-486-mediated regulation of muscular atrophy and exercise
D Qiu, Y Zhang, P Ni, Z Wang, L Yang, F Li - Journal of Physiology and …, 2024 - Springer
The objectives of this review were to understand the impact of microRNA-486 on
myogenesis and muscle atrophy, and the change of microRNA-486 following exercise, and …
myogenesis and muscle atrophy, and the change of microRNA-486 following exercise, and …
MicroRNA-542-3p targets Pten to inhibit the myoblasts proliferation but suppresses myogenic differentiation independent of targeted Pten
D Li, Y Yue, X Feng, W Lv, Y Fan, P Sha, T Zhao, Y Lin… - BMC genomics, 2024 - Springer
Background Non-coding RNA is a key epigenetic regulation factor during skeletal muscle
development and postnatal growth, and miR-542-3p was reported to be conserved and …
development and postnatal growth, and miR-542-3p was reported to be conserved and …
A human skeletal muscle stem/myotube model reveals multiple signaling targets of cancer secretome in skeletal muscle
Skeletal muscle dysfunction or reprogramming due to the effects of the cancer secretome is
observed in multiple malignancies. Although mouse models are routinely used to study …
observed in multiple malignancies. Although mouse models are routinely used to study …
Extracellular vesicle characteristics and microRNA content in cerebral palsy and typically developed individuals at rest and in response to aerobic exercise
IJ Vechetti, J Norrbom, B Alkner, E Hjalmarsson… - Frontiers in …, 2022 - frontiersin.org
In this study, the properties of circulating extracellular vesicles (EVs) were examined in
cerebral palsy (CP) and typically developed (TD) individuals at rest and after aerobic …
cerebral palsy (CP) and typically developed (TD) individuals at rest and after aerobic …
Mutant RAS-driven Secretome Causes Skeletal Muscle Defects in Breast Cancer
Cancer-induced skeletal muscle defects differ in severity between individuals with the same
cancer type. Cancer subtype-specific genomic aberrations are suggested to mediate these …
cancer type. Cancer subtype-specific genomic aberrations are suggested to mediate these …
[HTML][HTML] Unveiling the functional and evolutionary landscape of RNA editing in chicken using genomics and transcriptomics
The evolutionary and functional features of RNA editing are well studied in mammals,
cephalopods, and insects, but not in birds. Here, we integrated transcriptomic and whole …
cephalopods, and insects, but not in birds. Here, we integrated transcriptomic and whole …
The response of muscle and inflammation-related miRNAs to breast cancer and its treatment
Aim this study aims to evaluate the response of muscle-specific (miR-1, miR-133, miR-208,
miR-486, miR-499) and inflammation-related (miR-21, miR-146, and miR-155) miRNAs, well …
miR-486, miR-499) and inflammation-related (miR-21, miR-146, and miR-155) miRNAs, well …