Abstract Receptor-interacting protein 3 (Ripk3)-mediated necroptosis contributes to cardiac
ischaemia-reperfusion (IR) injury through poorly defined mechanisms. Our results …

High-density lipoproteins (HDL) are complex endogenous nanoparticles involved in
important functions such as reverse cholesterol transport and immunomodulatory activities …

Exosomes derived from human umbilical cord mesenchymal stem cells (HUCMSCs) were
helpful for injury repair, but whether HUCMSCs-derived exosomes could be encapsulated in …

LCZ696 blocks both angiotensin receptor type 1 (ATR1) and neprilysin (NEP), which are
intricate in the degradation of natriuretic peptides (NPs) and other endogenous peptides. It …

The long‐term prognosis of vascular restenosis after endovascular interventional treatment
is a critical challenge in a clinical setting. Over‐production of reactive oxygen species (ROS) …

Abstract Nitroxyl (HNO), one-electron reduced and protonated sibling of nitric oxide (NO), is
a potential regulator of cardiovascular functions. It produces positive inotropic, lusitropic …

Obesity is an epidemic public health problem that has progressively worsened in recent
decades and is associated with low-grade chronic inflammation (LGCI) in metabolic tissues …

Abstract Aims Eva-1 homologue 1 (Eva1a) is a novel protein involved in the regulation of
cardiac remodelling and plaque stability, but little is known about its role in re …

Atherosclerosis is a disease of increased oxidative stress characterized by protein and lipid
modifications in the vessel wall. One important oxidative pathway involves reactive …

Peptides are emerging as a promising candidate for therapeutic as well as diagnostic
applications within the domain of clinical and scientific research. They are recognized for …