Rational design of immunomodulatory hydrogels for chronic wound healing

M Kharaziha, A Baidya, N Annabi - Advanced Materials, 2021 - Wiley Online Library
With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …

Cancer nanomedicine toward clinical translation: Obstacles, opportunities, and future prospects

P Zhang, Y Xiao, X Sun, X Lin, S Koo, AV Yaremenko… - Med, 2023 - cell.com
With the integration of nanotechnology into the medical field at large, great strides have
been made in the development of nanomedicines for tackling different diseases, including …

[HTML][HTML] Mesoporous silica nanoparticles for drug and gene delivery

Y Zhou, G Quan, Q Wu, X Zhang, B Niu, B Wu… - … pharmaceutica sinica B, 2018 - Elsevier
Mesoporous silica nanoparticles (MSNs) are attracting increasing interest for potential
biomedical applications. With tailored mesoporous structure, huge surface area and pore …

The delivery of therapeutic oligonucleotides

RL Juliano - Nucleic acids research, 2016 - academic.oup.com
The oligonucleotide therapeutics field has seen remarkable progress over the last few years
with the approval of the first antisense drug and with promising developments in late stage …

Diverse applications of nanomedicine

B Pelaz, C Alexiou, RA Alvarez-Puebla, F Alves… - ACS …, 2017 - ACS Publications
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …

Recent advances of cocktail chemotherapy by combination drug delivery systems

Q Hu, W Sun, C Wang, Z Gu - Advanced drug delivery reviews, 2016 - Elsevier
Combination chemotherapy is widely exploited for enhanced cancer treatment in the clinic.
However, the traditional cocktail administration of combination regimens often suffers from …

A gene and drug co-delivery application helps to solve the short life disadvantage of RNA drug

M Li, Z Ma, M Peng, L Li, M Yin, S Yan, J Shen - Nano Today, 2022 - Elsevier
Novel green technology RNA pesticide has been put forward as a promising method for
plant protection, but the instability and short life disadvantage of double-stranded RNA …

Nanomedicine of synergistic drug combinations for cancer therapy–Strategies and perspectives

RX Zhang, HL Wong, HY Xue, JY Eoh… - Journal of Controlled …, 2016 - Elsevier
Nanomedicine of synergistic drug combinations has shown increasing significance in
cancer therapy due to its promise in providing superior therapeutic benefits to the current …

Duchenne muscular dystrophy: from diagnosis to therapy

MS Falzarano, C Scotton, C Passarelli, A Ferlini - Molecules, 2015 - mdpi.com
Duchenne muscular dystrophy (DMD) is an X-linked inherited neuromuscular disorder due
to mutations in the dystrophin gene. It is characterized by progressive muscle weakness and …

Virus-like nanoparticle as a co-delivery system to enhance efficacy of CRISPR/Cas9-based cancer immunotherapy

Q Liu, C Wang, Y Zheng, Y Zhao, Y Wang, J Hao… - Biomaterials, 2020 - Elsevier
Abstract The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-
associated protein 9 (Cas9) system holds great promise for the cancer gene therapy …