The relatively new field of phylogenomics is beginning to reveal the potential of genomic
data for evolutionary studies. As the cost of whole genome sequencing falls, anticipation of …

One of the challenges in the Comparative Genomics field is to infer how close two
organisms are based on the similarities and differences between their genetic materials …

As genomes evolve, they undergo large-scale evolutionary processes that present a
challenge to sequence comparison not posed by short sequences. Recombination causes …

A comprehensive survey of a rapidly expanding field of combinatorial optimization,
mathematically oriented but offering biological explanations when required. From one cell to …

Genome Rearrangements In Man and Mouse (GRIMM) is a tool for analyzing
rearrangements of gene orders in pairs of unichromosomal and multichromosomal …

A comprehensive account of both basic and advanced material in phylogeny estimation,
focusing on computational and statistical issues. No background in biology or computer …

This article analyzes mammalian genome rearrangements at higher resolution than has
been published to date. We identify 3171 intervals, covering∼ 92% of the human genome …

Comparing complete animal mitochondrial genome sequences is becoming increasingly
common for phylogenetic reconstruction and as a model for genome evolution. Not only are …

The enormous complexity of biological systems at the molecular level must be answered
with powerful computational methods. Computational biology is a young field, but has seen …

Sorting permutations by transpositions is an important problem in genome rearrangements.
A transposition is a rearrangement operation in which a segment is cut out of the …