Despite declines in heart failure morbidity and mortality with current therapies,
rehospitalization rates remain distressingly high, substantially affecting individuals, society …

Behavioural traits in mammals are influenced by environmental factors, which can interact
with the genome and modulate its activity by complex molecular interplay. Environmental …

Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …

Monozygous twins share a common genotype. However, most monozygotic twin pairs are
not identical; several types of phenotypic discordance may be observed, such as differences …

Hematopoietic stem cell (HSC) populations change with aging, but the extent to which this is
caused by qualitative versus quantitative alterations in HSC subtypes is unclear. Using …

Macroautophagy/autophagy is primarily accountable for the degradation of damaged
organelles and toxic macromolecules in the cells. Regarding the essential function of …

A male sex bias has emerged in the COVID-19 pandemic, fitting to the sex-biased pattern in
other viral infections. Males are 2.84 times more often admitted to the ICU and mortality is …

Despite an enormous research effort, most cases of late-onset Alzheimer's disease (LOAD)
still remain unexplained and the current biomedical science is still a long way from the …

Background X chromosome inactivation is the epigenetic silencing of the majority of the
genes on one of the X chromosomes in XX therian mammals. In humans, approximately …

Endometriosis is a common gynecologic disorder with an enigmatic etiopathogenesis.
Although it has been proposed that endometriosis is a hormonal disease, an autoimmune …