Abstract Background and Objective Advanced material models and material characterization
of soft biological tissues play an essential role in pre-surgical planning for vascular surgeries …

Aim Abdominal aortic aneurysms (AAA) is a life-threatening weakening and expansion of
the abdominal aorta due to inflammatory cell infiltration and gradual degeneration of …

Thoracic aortic aneurysm (TAA) is characterized by dilation of the aorta that can lead to
dissection or rupture. Degradation of elastic fibers is a consistent histopathological feature of …

This study was aimed at generating data for designing a potential method to prevent the
rupture of the abdominal aortic aneurysm (AAA). We found that the mechanical strength and …

Background: The aim of this systematic review was to pool evidence from studies testing if
pentagalloyl glucose (PGG) limited aortic expansion in animal models of abdominal aortic …

The suppression of abdominal aortic aneurysm (AAA) growth by nonsurgical therapy is
currently not an option, and AAA is considered an irreversible destructive disease. The …

Objective The goal of the present study was to test the safety and efficacy of chemical
stabilization of the arterial extracellular matrix as a novel nonoperative treatment of …

Background Elastic fibers are composed primarily of the protein elastin and they provide
reversible elasticity to the large arteries. Degradation of elastic fibers is a common …

Background Regional mechanical characterization of pulmonary arteries can be useful in
the development of computational models of pulmonary arterial mechanics. Objective We …

Pentagalloyl glucose (PGG) is currently being investigated as a non-surgical treatment for
abdominal aortic aneurysms (AAAs); however, the molecular mechanisms of action of PGG …