The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and …

CE Cooper, GC Brown - Journal of bioenergetics and biomembranes, 2008 - Springer
The four gases, nitric oxide (NO), carbon monoxide (CO), hydrogen sulfide (H 2 S) and
hydrogen cyanide (HCN) all readily inhibit oxygen consumption by mitochondrial …

[HTML][HTML] What is the real physiological NO concentration in vivo?

CN Hall, J Garthwaite - Nitric oxide, 2009 - Elsevier
Clarity about the nitric oxide (NO) concentrations existing physiologically is essential for
developing a quantitative understanding of NO signalling, for performing experiments with …

Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans

SJ Bailey, P Winyard, A Vanhatalo… - Journal of applied …, 2009 - journals.physiology.org
Pharmacological sodium nitrate supplementation has been reported to reduce the O 2 cost
of submaximal exercise in humans. In this study, we hypothesized that dietary …

Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver

MR Duranski, JJM Greer, A Dejam… - The Journal of …, 2005 - Am Soc Clin Investig
Nitrite represents a circulating and tissue storage form of NO whose bioactivation is
mediated by the enzymatic action of xanthine oxidoreductase, nonenzymatic …

The effect of nitric oxide on mitochondrial respiration

JJ Poderoso, K Helfenberger, C Poderoso - Nitric oxide, 2019 - Elsevier
This article reviews the interactions between nitric oxide (NO) and mitochondrial respiration.
Mitochondrial ATP synthesis is responsible for virtually all energy production in mammals …

[HTML][HTML] Cytochrome bd oxidase and bacterial tolerance to oxidative and nitrosative stress

A Giuffrè, VB Borisov, M Arese, P Sarti… - Biochimica et Biophysica …, 2014 - Elsevier
Cytochrome bd is a prokaryotic respiratory quinol: O 2 oxidoreductase, phylogenetically
unrelated to the extensively studied heme–copper oxidases (HCOs). The enzyme …

Nitric oxide inhibition of mitochondrial respiration and its role in cell death

GC Brown, V Borutaite - Free Radical Biology and Medicine, 2002 - Elsevier
NO or its derivatives (reactive nitrogen species: RNS) inhibit mitochondrial respiration in two
different ways:(i) an acute, potent, and reversible inhibition of cytochrome oxidase by NO in …

Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrine NO homeostasis

S Shiva, X Wang, LA Ringwood, X Xu… - Nature chemical …, 2006 - nature.com
Nitrite represents a bioactive reservoir of nitric oxide (NO) that may modulate vasodilation,
respiration and cytoprotection after ischemia-reperfusion injury. Although nitrite formation is …

Myoglobin: a scavenger of bioactive NO

U Flögel, MW Merx, A Gödecke… - Proceedings of the …, 2001 - National Acad Sciences
The present study explored the role of myoglobin (Mb) in cardiac NO homeostasis and its
functional relevance by employing isolated hearts of wild-type (WT) and myoglobin knockout …

The contribution of an imbalanced redox signalling to neurological and neurodegenerative conditions

JR Steinert, H Amal - Free Radical Biology and Medicine, 2023 - Elsevier
Nitric oxide and other redox active molecules such as oxygen free radicals provide essential
signalling in diverse neuronal functions, but their excess production and insufficient …