Superoxide anion chemistry—Its role at the core of the innate immunity

CMC Andrés, JM Pérez de la Lastra… - International journal of …, 2023 - mdpi.com
Classically, superoxide anion O2•− and reactive oxygen species ROS play a dual role. At
the physiological balance level, they are a by-product of O2 reduction, necessary for cell …

Superoxide dismutases and superoxide reductases

Y Sheng, IA Abreu, DE Cabelli, MJ Maroney… - Chemical …, 2014 - ACS Publications
Superoxide, O2•−, is formed in all living organisms that come in contact with air, and,
depending upon its biological context, it may act as a signaling agent, a toxic species, or a …

[HTML][HTML] Metalloproteins containing cytochrome, iron–sulfur, or copper redox centers

J Liu, S Chakraborty, P Hosseinzadeh, Y Yu… - Chemical …, 2014 - ACS Publications
Redox reactions play important roles in almost all biological processes, including
photosynthesis and respiration, which are two essential energy processes that sustain all life …

A post-genomic view of the ecophysiology, catabolism and biotechnological relevance of sulphate-reducing prokaryotes

R Rabus, SS Venceslau, L Wöhlbrand… - Advances in microbial …, 2015 - Elsevier
Dissimilatory sulphate reduction is the unifying and defining trait of sulphate-reducing
prokaryotes (SRP). In their predominant habitats, sulphate-rich marine sediments, SRP have …

Oxygen tolerance and detoxification mechanisms of highly enriched planktonic anaerobic ammonium-oxidizing (anammox) bacteria

S Okabe, S Ye, X Lan, K Nukada, H Zhang… - ISME …, 2023 - academic.oup.com
Oxygen is a key regulatory factor of anaerobic ammonium oxidation (anammox). Although
the inhibitory effect of oxygen is evident, a wide range of oxygen sensitivities of anammox …

How superoxide reductases and flavodiiron proteins combat oxidative stress in anaerobes

MC Martins, CV Romão, F Folgosa, PT Borges… - Free Radical Biology …, 2019 - Elsevier
Microbial anaerobes are exposed in the natural environment and in their hosts, even if
transiently, to fluctuating concentrations of oxygen and its derived reactive species, which …

Reductive elimination of superoxide: Structure and mechanism of superoxide reductases

AF Pinto, JV Rodrigues, M Teixeira - … et Biophysica Acta (BBA)-Proteins and …, 2010 - Elsevier
Superoxide anion is among the deleterious reactive oxygen species, towards which all
organisms have specialized detoxifying enzymes. For quite a long time, superoxide …

Rational Tuning of the Thiolate Donor in Model Complexes of Superoxide Reductase: Direct Evidence for a trans Influence in FeIII−OOR Complexes

F Namuswe, GD Kasper, AAN Sarjeant… - Journal of the …, 2008 - ACS Publications
Iron peroxide species have been identified as important intermediates in a number of
nonheme iron as well as heme-containing enzymes, yet there are only a few examples of …

Influence of the Nitrogen Donors on Nonheme Iron Models of Superoxide Reductase: High-Spin FeIII−OOR Complexes

F Namuswe, T Hayashi, Y Jiang… - Journal of the …, 2010 - ACS Publications
A new five-coordinate,(N4S (thiolate)) FeII complex, containing tertiary amine donors,[FeII
(Me4 [15] aneN4)(SPh)] BPh4 (2), was synthesized and structurally characterized as a …

Antioxidant defence systems in the protozoan pathogen Giardia intestinalis

D Mastronicola, M Falabella, E Forte, F Testa… - Molecular and …, 2016 - Elsevier
The microaerophilic protist Giardia intestinalis is the causative agent of giardiasis, one of the
most common intestinal infectious diseases worldwide. The pathogen lacks not only …