Adipose tissue is a widely distributed organ that plays a critical role in age-related
physiological dysfunctions as an important source of chronic sterile low-grade inflammation …

Metabolic dysfunction–associated steatotic liver disease (MASLD) is a growing global health
problem, affecting∼ 1 billion people. This condition is well established to have a heritable …

Diverse factors contribute to the limited clinical response to radiotherapy (RT) and
immunotherapy in metastatic non–small cell lung cancer (NSCLC), among which is the …

Psoriasis is a chronic autoimmune inflammatory skin disorder characterized by epidermal
hyperplasia and aberrant immune response. In addition to aberrant cytokine production …

Cardiovascular disease is the leading cause of death worldwide, and it commonly results
from atherosclerotic plaque progression. One of the increasingly recognized drivers of …

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
(CLD) worldwide and inflammation is key to its progression/resolution. As we have …

This work aimed to investigate the effect of aurantiamide (Aur) in promoting the M2
polarization of microglial cells to improve the cognitive ability of mice with Alzheimer's …

To find novel anti-inflammatory drugs, we screened anti-inflammatory compounds from 18
different types of Artemisia argyi seed extracts. The in vitro and in vivo anti-inflammatory …

Signal transducer and activator of transcription 6 (STAT6) promotes an anti-inflammatory
process by inducing the development of M2 macrophages. We investigated whether …

Sphingolipids are key molecules in inflammation and defense against pathogens. Their role
in dectin-1/TLR2-mediated responses is, however, poorly understood. This study …