LAMC2 as a prognostic biomarker in human cancer: a systematic review and meta-analysis

T Fu, JX Liu, J Xie, Z Gao, Z Yang - BMJ open, 2022 - bmjopen.bmj.com
Objectives Accumulating evidence suggested that the laminin γ2 (LAMC2) expression level
was upregulated in various cancers. However, the potential prognostic value of LAMC2 in …

Paradoxical roles of desmosomal components in head and neck cancer

YQ Liu, HY Zou, JJ Xie, WK Fang - Biomolecules, 2021 - mdpi.com
Desmosomes are intercellular adhesion complexes involved in various aspects of epithelial
pathophysiology, including tissue homeostasis, morphogenesis, and disease development …

CCND1-associated ceRNA network reveal the critical pathway of TPRG1-AS1-hsa-miR-363-3p-MYO1B as a prognostic marker for head and neck squamous cell …

Z Li, X Qiu, Q He, X Fu, F Ji, X Tian - Scientific Reports, 2023 - nature.com
Head and neck squamous cell carcinoma (HNSC) is one of the leading causes of cancer
death globally, yet there are few useful biomarkers for early identification and prognostic …

Novel human lymph node-derived matrix supports the adhesion of metastatic oral carcinoma cells

E Naakka, W Wahbi, R Tiikkaja, K Juurikka, T Sandvik… - BMC cancer, 2023 - Springer
Background 3D culture is increasingly used in cancer research, as it allows the growth of
cells in an environment that mimics in vivo conditions. Metastases are the primary cause of …

[HTML][HTML] Trichodermin inhibits the growth of oral cancer through apoptosis-induced mitochondrial dysfunction and HDAC-2-mediated signaling

HL Chen, YH Lo, CL Lin, TH Lee, W Leung… - Biomedicine & …, 2022 - Elsevier
Trichodermin (TCD), a trichothecene first isolated from marine Trichoderma viride, is an
inhibitor of eukaryotic protein synthesis. However, the potential effects of TCD on human oral …

RFC4 promotes the progression and growth of Oral Tongue squamous cell carcinoma in vivo and vitro

J Zhang, L Wang, X Xie - Journal of clinical laboratory analysis, 2021 - Wiley Online Library
Objective Currently, many studies have found that RFC4 was up‐regulated in various
cancers, and related to the progression and development. While the effects of RFC4 in oral …

Invasion-Associated Reorganization of Laminin 332 in Oral Squamous Cell Carcinomas: The Role of the Laminin γ2 Chain in Tumor Biology, Diagnosis, and Therapy

A Berndt, N Gaßler, M Franz - Cancers, 2022 - mdpi.com
Simple Summary The destructive growth of carcinomas is associated with crossing the
border between the epithelial and the connective tissue parts of an organ. One component …

Prognostic impact of the loss of E-cadherin and de novo expression of N-cadherin at the invasive front of primary and recurrent oral squamous cell carcinoma

SG Hakim, C Taubitz, S Hoppe, D Steller… - Frontiers in …, 2023 - frontiersin.org
The epithelial-mesenchymal transition (EMT) is a biological mechanism in multiple
pathophysiological diseases. Related alterations in cadherin expression play a crucial role …

ITGA5 is associated with prognosis marker and immunosuppression in head and neck squamous cell carcinoma

J Liu, Y Wang, X Chen, X Chen, M Zhang - Diagnostic Pathology, 2024 - Springer
Background Head and neck squamous cell carcinoma (HNSCC) is a major tumor that
seriously threatens the health of the head and neck or mucosal system. It is manifested as a …

Desmoglein-2 as a cancer modulator: friend or foe?

KK Myo Min, CB Ffrench, BJ McClure, M Ortiz… - Frontiers in …, 2023 - frontiersin.org
Desmoglein-2 (DSG2) is a calcium-binding single pass transmembrane glycoprotein and a
member of the large cadherin family. Until recently, DSG2 was thought to only function as a …