Simple Summary Survival after diagnosis of metastatic uveal melanoma has not significantly
improved over decades, most patients die within a year from diagnosis. Uveal melanoma is …

Approximately 90% of uveal melanomas develop in the choroid, with the remainder arising
in the ciliary body or the iris. The treatment of uveal melanoma is aimed at conserving the …

Importance Despite high rates of local tumor control in patients who are treated for uveal
melanoma, most patients will eventually die of metastasis. When metastasis develops, the …

Purpose To investigate if the interval between diagnosis and treatment of posterior uveal
melanoma (UM) is associated with metastatic death. Design Retrospective, single-center …

Uveal melanoma (UM) is a rare tumour with a high propensity to metastasize. Although no
effective treatment for metastases yet exists, prognostication in UM is relevant for patient …

The prognostic implications of delaying treatment for primary uveal melanoma remain
debated. We evaluate the impact of choroidal nevi and melanoma doubling times on …

Purpose: The American Joint Committee on Cancer (AJCC) staging system has been
validated for use as a prognostic parameter in uveal melanoma (UM). We studied whether …

About 50% of patients with choroidal melanoma develop metastatic disease, despite
successful eradication of the primary tumor. Patient care is complicated by the fact that we …

PURPOSE Validated and accurate prognostic testing is critical for precision medicine in
uveal melanoma (UM). Our aims were to (1) prospectively validate an integrated prognostic …

Purpose The Cancer Genome Atlas (TCGA) classification has been validated for uveal
melanoma (UM) prognostication. We applied TCGA classification to UM biopsied using fine …