Recent studies have begun to scrutinize the presynaptic machinery and vesicle populations
that give rise to action potential evoked and spontaneous forms of neurotransmitter release …

The revolution in genetic technology has ushered in a new age for our understanding of the
underlying causes of neurodevelopmental, neuromuscular and neurodegenerative …

The G protein‐coupled receptor (GPCR) Proteolysis Site (GPS) of cell‐adhesion GPCRs
and polycystic kidney disease (PKD) proteins constitutes a highly conserved autoproteolysis …

Latrophilin 1 (LPH1), a neuronal receptor of α-latrotoxin, is implicated in neurotransmitter
release and control of presynaptic Ca2+. As an “adhesion G-protein-coupled receptor,” …

Recent studies suggest that synaptic vesicles (SVs) giving rise to spontaneous
neurotransmission are distinct from those that carry out evoked release. However, the …

Fibronectin leucine-rich repeat transmembrane proteins (FLRTs) are cell-adhesion
molecules with emerging functions in cortical development and synapse formation. Their …

Reelin is a glycoprotein that is critical for proper layering of neocortex during development
as well as dynamic regulation of glutamatergic postsynaptic signaling in mature synapses …

The trans-synaptic interaction of the cell-adhesion molecules teneurins (TENs) with
latrophilins (LPHNs/ADGRLs) promotes excitatory synapse formation when LPHNs …

Neuronal communication relies on chemical synaptic transmission for information transfer
and processing. Chemical neurotransmission is initiated by synaptic vesicle fusion with the …

Developing neurons form synapses at a high rate. Synaptic transmission is very energy-
demanding and likely requires ATP production by mitochondria nearby. Mitochondria might …