Macrophages in the cochlea; an immunological link between risk factors and progressive hearing loss
K Hough, CA Verschuur, C Cunningham, TA Newman - Glia, 2022 - Wiley Online Library
Macrophages are abundant in the cochlea; however, their role in hearing loss is not well
understood. Insults to the cochlea, such as noise or insertion of a cochlear implant, cause an …
understood. Insults to the cochlea, such as noise or insertion of a cochlear implant, cause an …
Emerging approaches for restoration of hearing and vision
Impairments of vision and hearing are highly prevalent conditions limiting the quality of life
and presenting a major socioeconomic burden. For a long time, retinal and cochlear …
and presenting a major socioeconomic burden. For a long time, retinal and cochlear …
Frequency map for the human cochlear spiral ganglion: implications for cochlear implants
O Stakhovskaya, D Sridhar, BH Bonham… - Journal for the …, 2007 - Springer
The goals of this study were to derive a frequency–position function for the human cochlear
spiral ganglion (SG) to correlate represented frequency along the organ of Corti (OC) to …
spiral ganglion (SG) to correlate represented frequency along the organ of Corti (OC) to …
Hearing loss and vestibular schwannoma: new insights into Schwann cells implication
T Mohamed, V Melfi, A Colciago, V Magnaghi - Cell Death & Disease, 2023 - nature.com
Hearing loss (HL) is the most common and heterogeneous disorder of the sensory system,
with a large morbidity in the worldwide population. Among cells of the acoustic nerve (VIII …
with a large morbidity in the worldwide population. Among cells of the acoustic nerve (VIII …
[HTML][HTML] Anatomical basis of drug delivery to the inner ear
The isolated anatomical position and blood-labyrinth barrier hampers systemic drug delivery
to the mammalian inner ear. Intratympanic placement of drugs and permeation via the round …
to the mammalian inner ear. Intratympanic placement of drugs and permeation via the round …
[HTML][HTML] Translational and interdisciplinary insights into presbyacusis: a multidimensional disease
There are multiple etiologies and phenotypes of age-related hearing loss or presbyacusis. In
this review we summarize findings from animal and human studies of presbyacusis …
this review we summarize findings from animal and human studies of presbyacusis …
Application of mouse models to research in hearing and balance
KK Ohlemiller, SM Jones, KR Johnson - … of the Association for Research in …, 2016 - Springer
Laboratory mice (Mus musculus) have become the major model species for inner ear
research. The major uses of mice include gene discovery, characterization, and …
research. The major uses of mice include gene discovery, characterization, and …
Finite element analysis and three-dimensional reconstruction of tonotopically aligned human auditory fiber pathways: a computational environment for modeling …
The application of cochlear implants can be studied with computational models. The
electrical potential distribution induced by an implanted device is evaluated with a volume …
electrical potential distribution induced by an implanted device is evaluated with a volume …
Use it or lose it? Lessons learned from the developing brains of children who are deaf and use cochlear implants to hear
In the present paper, we review what is currently known about the effects of deafness on the
developing human auditory system and ask: Without use, does the immature auditory …
developing human auditory system and ask: Without use, does the immature auditory …
Mouse methods and models for studies in hearing
KK Ohlemiller - The Journal of the Acoustical Society of America, 2019 - pubs.aip.org
Laboratory mice have become the dominant animal model for hearing research. The mouse
cochlea operates according to standard “mammalian” principles, uses the same cochlear …
cochlea operates according to standard “mammalian” principles, uses the same cochlear …