Soft‐tissue sarcoma in adults: an update on the current state of histiotype‐specific management in an era of personalized medicine

AC Gamboa, A Gronchi… - CA: a cancer journal for …, 2020 - Wiley Online Library
Soft‐tissue sarcomas (STS) are rare tumors that account for 1% of all adult malignancies,
with over 100 different histologic subtypes occurring predominately in the trunk, extremity …

Clinical and molecular spectrum of liposarcoma

ATJ Lee, K Thway, PH Huang… - Journal of Clinical …, 2018 - ascopubs.org
Liposarcomas are rare malignant tumors of adipocytic differentiation. The classification of
liposarcomas into four principal subtypes reflects the distinct clinical behavior, treatment …

Soft tissue and visceral sarcomas: ESMO–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

PG Casali, N Abecassis, S Bauer, R Biagini… - Annals of …, 2018 - annalsofoncology.org
Soft tissue sarcomas (STSs) gather over 80 histological entities, with even more molecular
subsets, characterised by a low to very low incidence in all populations. The majority of …

NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma …

S Bonvalot, PL Rutkowski, J Thariat, S Carrère… - The Lancet …, 2019 - thelancet.com
Background Pathological complete response to preoperative treatment in adults with soft-
tissue sarcoma can be achieved in only a few patients receiving radiotherapy. This phase 2 …

Soft tissue sarcoma, version 2.2018, NCCN clinical practice guidelines in oncology

M Von Mehren, RL Randall, RS Benjamin… - Journal of the National …, 2018 - jnccn.org
Soft tissue sarcomas (STS) are rare solid tumors of mesenchymal cell origin that display a
heterogenous mix of clinical and pathologic characteristics. STS can develop from fat …

Management of primary retroperitoneal sarcoma (RPS) in the adult: an updated consensus approach from the Transatlantic Australasian RPS Working Group

CJ Swallow, DC Strauss, S Bonvalot… - Annals of surgical …, 2021 - Springer
Background Retroperitoneal soft tissue sarcomas comprise a heterogeneous group of rare
tumors of mesenchymal origin that include several well-defined histologic subtypes. In 2015 …

Neoadjuvant chemotherapy in high-risk soft tissue sarcomas: final results of a randomized trial from Italian (ISG), Spanish (GEIS), French (FSG), and Polish (PSG) …

A Gronchi, E Palmerini, V Quagliuolo… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To determine whether the administration of histology-tailored neoadjuvant
chemotherapy (HT) was superior to the administration of standard anthracycline plus …

Effect of neoadjuvant chemotherapy plus regional hyperthermia on long-term outcomes among patients with localized high-risk soft tissue sarcoma: the EORTC 62961 …

RD Issels, LH Lindner, J Verweij, R Wessalowski… - JAMA …, 2018 - jamanetwork.com
Importance Patients with soft tissue sarcoma are at risk for local recurrence and distant
metastases despite optimal local treatment. Preoperative anthracycline plus ifosfamide …

Objective response rate among patients with locally advanced or metastatic sarcoma treated with talimogene laherparepvec in combination with pembrolizumab: a …

CM Kelly, CR Antonescu, T Bowler, R Munhoz… - JAMA …, 2020 - jamanetwork.com
Importance Patients with advanced sarcoma have limited treatment options. Talimogene
laherparepvec (T-VEC) has been shown to increase tumor-specific immune activation via …

Uterine leiomyosarcoma: A review of the literature and update on management options

ME Roberts, JT Aynardi, CS Chu - Gynecologic Oncology, 2018 - Elsevier
Uterine leiomyosarcoma is the most common type of uterine sarcoma. It is an extremely
aggressive malignancy associated with a poor overall prognosis. Women affected may vary …