Plasmid evolution in carbapenemase‐producing Enterobacteriaceae: a review

K Kopotsa, J Osei Sekyere… - Annals of the New York …, 2019 - Wiley Online Library
Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

Plasmid-mediated resistance is going wild

M Dolejska, CC Papagiannitsis - Plasmid, 2018 - Elsevier
Multidrug resistant (MDR) Gram-negative bacteria have been increasingly reported in
humans, companion animals and farm animals. The growing trend of plasmid-mediated …

Genomic dissection of endemic carbapenem resistance reveals metallo-beta-lactamase dissemination through clonal, plasmid and integron transfer

N Macesic, J Hawkey, B Vezina, JA Wisniewski… - Nature …, 2023 - nature.com
Infections caused by metallo-beta-lactamase-producing organisms (MBLs) are a global
health threat. Our understanding of transmission dynamics and how MBLs establish …

Genomic dynamics of species and mobile genetic elements in a prolonged blaIMP-4-associated carbapenemase outbreak in an Australian hospital

A Kizny Gordon, HTT Phan, SI Lipworth… - Journal of …, 2020 - academic.oup.com
Background Hospital outbreaks of carbapenemase-producing organisms, such as bla IMP-4-
containing organisms, are an increasing threat to patient safety. Objectives To investigate …

Epidemic HI2 Plasmids Mobilising the Carbapenemase Gene blaIMP-4 in Australian Clinical Samples Identified in Multiple Sublineages of Escherichia coli ST216 …

H Tarabai, ER Wyrsch, I Bitar, M Dolejska… - Microorganisms, 2021 - mdpi.com
Escherichia coli ST216, including those that carry bla KPC-2, bla FOX-5, bla CTX-M-15 and
mcr-1, have been linked to wild and urban-adapted birds and the colonisation of hospital …

Coexistence of a novel NDM-1-encoding MDR plasmid and an IMP-4-encoding IncN-IncU hybrid plasmid in a clinical isolate of Citrobacter freundii BC73

N Liu, B Tang, H Wang, X Chen, P Wen… - Frontiers in …, 2024 - frontiersin.org
Objectives To investigate the genetic characteristics and transmission mechanism of the
NDM-1-, IMP-4-, and SHV-12-producing multidrug-resistant (MDR) clinical isolate …

Whole Genome Sequencing Analysis of Porcine Faecal Commensal Escherichia coli Carrying Class 1 Integrons from Sows and Their Offspring

T Zingali, CJ Reid, TA Chapman, D Gaio, M Liu… - Microorganisms, 2020 - mdpi.com
Intensive pig production systems often rely on the use of antimicrobials and heavy metal
feed additives to maintain animal health and welfare. To gain insight into the carriage of …

Characterization of a NDM-1- Encoding Plasmid pHFK418-NDM From a Clinical Proteus mirabilis Isolate Harboring Two Novel Transposons, Tn6624 and Tn6625

D Dong, M Li, Z Liu, J Feng, N Jia, H Zhao… - Frontiers in …, 2019 - frontiersin.org
Acquisition of the bla NDM–1 gene by Proteus mirabilis is a concern because it already has
intrinsic resistance to polymyxin E and tigecycline antibiotics. Here, we describe a P. mirabili …

Characterization of a blaIMP-4-carrying plasmid from Enterobacter cloacae of swine origin

Y Zhu, W Zhang, S Schwarz, C Wang… - Journal of …, 2019 - academic.oup.com
Objectives To characterize an MDR bla IMP-4-harbouring plasmid from Enterobacter
cloacae EC62 of swine origin in China. Methods Plasmid pIMP-4-EC62 from E. cloacae …

Molecular Characterization of blaIMP4-Carrying Enterobacterales in Henan Province of China

W Liu, H Dong, T Yan, X Liu, J Cheng, C Liu… - Frontiers in …, 2021 - frontiersin.org
Carbapenem-resistant Enterobacterales (CRE) pose a serious threat to clinical
management and public health. We investigated the molecular characteristics of 12 IMP-4 …