Prostate cancer is a global health problem, but incidence varies considerably across
different continents. Asia is traditionally considered a low-incidence area, but the incidence …

The incidence of prostate cancer has been increasing worldwide in recent years. The
GLOBOCAN project showed that prostate cancer was the second most frequently diagnosed …

Homeobox (HOX) transcription factors, encoded by a subset of homeodomain superfamily
genes, play pivotal roles in many aspects of cellular physiology, embryonic development …

Racial differences of prostate cancer incidence and mortality among Asian, Black, and
Caucasian men have been known, however, comprehensive update of this topic is not yet …

The Hox genes are an evolutionarily conserved family of genes, which encode a class of
important transcription factors that function in numerous developmental processes …

Breast cancer develops in the mammary glands during mammalian adulthood and is
considered the second most common type of human carcinoma and the most incident and …

Background Genetic testing has been conducted in patients with prostate cancer (PCa)
using multigene panels, but no centralized guidelines for genetic testing exist. To overcome …

Prostate cancer exerts a greater toll on African American men than on White men of
European descent (hereafter referred to as European American men): the disparity in …

Background The prognostic significance of germline variants in homologous recombination
repair genes in advanced prostate cancer (PCa), especially with regard to hormonal …

The androgen receptor (AR) is a critical therapeutic target in prostate cancer that responds
to antagonists in primary disease, but inevitably becomes reactivated, signaling onset of the …