Actions of thyroid hormones and thyromimetics on the liver

RA Sinha, E Bruinstroop, PM Yen - Nature Reviews Gastroenterology & …, 2024 - nature.com
Thyroid hormones (triiodothyronine and thyroxine) are pivotal for metabolic balance in the
liver and entire body. Dysregulation of the hypothalamus–pituitary–thyroid axis can …

Genetic background strongly influences the impact of carrying the Thr92Ala-DIO2 polymorphism in the male mouse

G Gabriel de Almeida, AP Bolin, A Batistuzzo… - …, 2024 - academic.oup.com
About half of the world population carries at least one allele of the Ala92-DIO2, which slows
down the activity of the type 2 deiodinase (D2), the enzyme that activates T4 to T3. Carrying …

Genetic Background Strongly Influences the Impact of Carrying the Thr92Ala-DIO2 Polymorphism in the Male Mouse

G Gabriel de Almeida, AP Bolin, A Batistuzzo… - …, 2024 - academic.oup.com
About half of the world population carries at least one allele of the Ala92-DIO2, which slows
down the activity of the type 2 deiodinase (D2), the enzyme that activates T4 to T3. Carrying …

Inhibition of type 3 iodothyronine deiodinase enhances differentiation of human induced pluripotent stem cells to β cells

A Maruoka, A Kimura, F Hattori, H Hitomi, K Osafune… - 2024 - researchsquare.com
Intracellular triiodothyronine (T3) level is up-regulated by type 2 iodothyronine deiodinase
(Dio2), which converts thyroxine (T4) to T3, or is down-regulated by type 3 iodothyronine …

[引用][C] The growing complexity of the control of the hypothalamic pituitary thyroid axis and brown adipose tissue by leptin

RH Costa-e-Sousa, VL Brooks - 2024 - Elsevier