Chiral phosphoric acids: a chiral lobby for enantioselective C–H activation

D Chandra, U Sharma - Chemical Communications, 2023 - pubs.rsc.org
Enantioselective C–H activation is one of the promising methods to obtain enantiopure
molecules in high enantiomeric excess with excellent control of regio and chemo-selectivity …

Recent advances in transition-metal-catalyzed directed C–H alkenylation with maleimides

SL Liu, C Ye, X Wang - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
Transition-metal-catalyzed directed C–H alkenylation with maleimides has attracted much
attention in recent years, as maleimide core moieties are present in various natural products …

Chiral transient ligand enabled enantioselective synthesis of atropisomers decorated with unactivated olefins via a palladium-catalyzed C–H olefination

V Arjun, M Jeganmohan - Organic Letters, 2023 - ACS Publications
Herein, atroposelective synthesis of axially chiral biaryls with unactivated olefins by a
palladium-catalyzed C–H olefination using a chiral transient directing group strategy has …

Iridium-Catalyzed Regiodivergent Atroposelective C–H Alkylation of Heterobiaryls with Alkenes

M Xiong, Z Yan, SC Chen, J Tang, F Yang… - ACS Catalysis, 2024 - ACS Publications
The atroposelective direct C–H alkylation of heterobiaryls with simple alkenes represents a
challenging and underexplored frontier. Herein we report an iridium (I)-catalyzed …

C− H Functionalization of Aldehydes and Ketones with Transient Directing Groups: Recent Developments

H Amistadi‐Revol, S Liu… - European Journal of …, 2023 - Wiley Online Library
In order to directly functionalize C− H bonds of complex molecules and, in particular, to
control the regioselectivity of the reaction, a wide range of directing groups has been used …

Chemo selective CH alkylation of isoquinolones with maleimides: A combined experimental and computational case study

D Chandra, N Kumar, P Gupta, U Sharma - Molecular Catalysis, 2023 - Elsevier
A comparative study of C8-alkylation of isoquinolone with maleimides is reported under
different catalytical systems. Among different catalytical systems, Ru and Rh catalysts were …

Rhodium‐Catalyzed C8‐Alkenylation of Isoquinolones with Maleimides

Manisha, D Chandra, U Sharma - European Journal of Organic …, 2023 - Wiley Online Library
An efficient Rh (III)‐catalyzed C− H alkenylation of N‐protected isoquinolone with
maleimides is reported. The carbonyl group of isoquinolone acts as an inherent directing …

Palladium-Catalyzed Allylic Alkylation Reactions of Nucleophilic Allenones: Asymmetric Allylic Alkylation, Z/E Divergent Allylic Alkylation, and [5 + 2] Annulation

W Wang, Y Hu, K Li, J Xu, C Zhang, L Zhou, L Zhu… - ACS …, 2024 - ACS Publications
Metal-catalyzed allenylic substitution reactions where allenes serve as electrophilic
precursors have been recognized as a rapid way for novel allene construction. On the …

Synthesis of axially chiral biaryls via Pd (ii)-catalysed direct C (sp 2)–H arylation

D Parmar, R Kumar, AK Sharma… - Organic Chemistry …, 2024 - pubs.rsc.org
Herein, a concise protocol for the construction of axially chiral biaryls via Pd-catalysed direct
C–H arylation of 1-arylisoquinoline N-oxides through kinetic resolution using a commercially …

Co (III)-Catalyzed Regioselective Functionalization of Isoquinolones with Naphthoquinones

T Sharma, Sumit, Sachin, D Chandra, SS Gupta… - Organic …, 2024 - ACS Publications
A strategy for Co (III)-catalyzed C (sp2)–H alkenylation of N-protected isoquinolones with 1,
4-naphthoquinones has been disclosed. The developed protocol was efficiently applied for …