Anti-Trypanosoma cruzi Properties of Sesquiterpene Lactones Isolated from Stevia spp.: In Vitro and In Silico Studies

J Borgo, OG Elso, J Gomez, M Coll, CAN Catalán… - Pharmaceutics, 2023 - mdpi.com
Stevia species (Asteraceae) have been a rich source of terpenoid compounds, mainly
sesquiterpene lactones, several of which show antiprotozoal activity. In the search for new …

Structural New Data for Mitochondrial Peroxiredoxin From Trypanosoma cruzi Show High Similarity With Human Peroxiredoxin 3: Repositioning Thiostrepton as …

L Rivera-Santiago, I Martínez… - Frontiers in Cellular …, 2022 - frontiersin.org
Trypanosoma cruzi, the causal agent of Chagas disease, has peroxiredoxins (PRXs)
expressed in all stages of the parasite and whose function is to detoxify oxidizing agents …

Sesquiterpenes from Inula macrophylla and their anti-neuroinflammatory activity

R Ma, B Komilov, CB Wang, KA Eshbakova… - Phytochemistry …, 2024 - Elsevier
A new sesquiterpene lactone dimer (1) and a new eremophilane sesquiterpene (4) together
with nine known sesquiterpenes have been characterized from Inula macrophylla. The …

Oxonitrogenated Derivatives of Eremophilans and Eudesmans: Antiproliferative and Anti-Trypanosoma cruzi Activity

MF Beer, GF Reta, A Puerta, AE Bivona, AS Alberti… - Molecules, 2022 - mdpi.com
Cancer is one of the most important causes of death worldwide. Solid tumors represent the
vast majority of cancers (> 90%), and the chemotherapeutic agents used for their treatment …