Anecdotal evidence that cannabis preparations have medical benefits together with the
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …

Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

The cannabinoid system is known to be important in neuronal regulation, but is also capable
of modulating immune function. Although the CNS resident microglial cells have been …

Endocannabinoids are released after brain injury and believed to attenuate neuronal
damage by binding to CB 1 receptors and protecting against excitotoxicity. Such excitotoxic …

2-Arachidonoylglycerol (2-AG) is a unique molecular species of monoacylglycerol isolated
in 1995 from rat brain and canine gut as an endogenous ligand for the cannabinoid …

Multiple sclerosis is the most common inflammatory demyelinating disease of the central
nervous system, caused by an autoimmune response against myelin that eventually leads to …

In the last few decades, endocannabinoids, plant-derived cannabinoids and synthetic
cannabinoids have received growing interest as treatment options in neurodegenerative …

The endocannabinoid signaling system (eCBSS) is composed of cannabinoid (CB)
receptors, their endogenous ligands (the endocannabinoids, eCB) and the enzymes that …

Endocannabinoid levels appear to be transiently elevated as an adaptive reaction to re-
establish normal homeostasis when this is acutely and pathologically perturbed. In some …

Lipids, defined by low solubility in water and high solubility in nonpolar solvents, can be
classified into fatty acids, glycerolipids, glycerophospholipids, sphingolipids, and sterols …