Immunomodulatory properties of human breast milk: microRNA contents and potential epigenetic effects

MMM Hatmal, MAI Al-Hatamleh, AN Olaimat, W Alshaer… - Biomedicines, 2022 - mdpi.com
Infants who are exclusively breastfed in the first six months of age receive adequate
nutrients, achieving optimal immune protection and growth. In addition to the known …

Association of prenatal alcohol exposure with offspring DNA methylation in mammals: a systematic review of the evidence

M Bestry, M Symons, A Larcombe, E Muggli… - Clinical …, 2022 - Springer
Background Prenatal alcohol exposure (PAE) is associated with a range of adverse
offspring neurodevelopmental outcomes. Several studies suggest that PAE modifies DNA …

DNA methylation as a predictor of fetal alcohol spectrum disorder

AA Lussier, AM Morin, JL MacIsaac, J Salmon… - Clinical …, 2018 - Springer
Background Fetal alcohol spectrum disorder (FASD) is a developmental disorder that
manifests through a range of cognitive, adaptive, physiological, and neurobiological deficits …

Prenatal alcohol exposure: profiling developmental DNA methylation patterns in central and peripheral tissues

AA Lussier, TS Bodnar, M Mingay, AM Morin… - Frontiers in …, 2018 - frontiersin.org
Background: Prenatal alcohol exposure (PAE) can alter the development of neurobiological
systems, leading to lasting neuroendocrine, neuroimmune, and neurobehavioral deficits …

Maternal choline supplementation in a rat model of periconceptional alcohol exposure: Impacts on the fetus and placenta

SE Steane, AM Fielding, NL Kent… - Alcoholism: Clinical …, 2021 - Wiley Online Library
Background Maternal choline supplementation in rats can ameliorate specific neurological
and behavioral abnormalities caused by alcohol exposure during pregnancy. We tested …

Prenatal adversity alters the epigenetic profile of the prefrontal cortex: sexually dimorphic effects of prenatal alcohol exposure and food-related stress

AA Lussier, TS Bodnar, M Moksa, M Hirst, MS Kobor… - Genes, 2021 - mdpi.com
Prenatal adversity or stress can have long-term consequences on developmental
trajectories and health outcomes. Although the biological mechanisms underlying these …

DNA methylation signature on phosphatidylethanol, not on self-reported alcohol consumption, predicts hazardous alcohol consumption in two distinct populations

X Liang, AC Justice, K So-Armah, JH Krystal… - Molecular …, 2021 - nature.com
The process of diagnosing hazardous alcohol drinking (HAD) is based on self-reported data
and is thereby vulnerable to bias. There has been an interest in developing epigenetic …

Prevalence and patterns of prenatal alcohol exposure in Australian cohort and cross-sectional studies: a systematic review of data collection approaches

SL Young, SE Steane, NL Kent, N Reid… - International Journal of …, 2022 - mdpi.com
This study sought to determine data collection approaches in Australian cohort studies and
explore the potential impact on reported prenatal alcohol exposure (PAE) prevalence and …

Investigating the influence of perinatal nicotine and alcohol exposure on the genetic profiles of dopaminergic neurons in the VTA using miRNA–mRNA analysis

T Kazemi, S Huang, NG Avci, CMK Waits, YM Akay… - Scientific reports, 2020 - nature.com
Nicotine and alcohol are two of the most commonly used and abused recreational drugs, are
often used simultaneously, and have been linked to significant health hazards. Furthermore …

Cohort Profile: The Triple B Pregnancy Cohort Study: A longitudinal study of the relationship between alcohol, tobacco and other substance use during pregnancy and …

D Hutchinson, J Wilson, S Allsop, E Elliott… - International journal …, 2018 - academic.oup.com
Summary The Triple B Pregnancy Cohort Study investigates the effects of parental alcohol,
tobacco and other substance use on infant development and family functioning. The study …