Calcium and mitochondria in the regulation of cell death
S Orrenius, V Gogvadze, B Zhivotovsky - Biochemical and biophysical …, 2015 - Elsevier
The calcium ion has long been known to play an important role in cell death regulation.
Hence, necrotic cell death was early associated with intracellular Ca 2+ overload, leading to …
Hence, necrotic cell death was early associated with intracellular Ca 2+ overload, leading to …
[HTML][HTML] Cell death as a result of calcium signaling modulation: A cancer-centric prospective
Abstract Calcium ions (Ca 2+) and the complex regulatory system governed by Ca 2+
signaling have been described to be of crucial importance in numerous aspects related to …
signaling have been described to be of crucial importance in numerous aspects related to …
Molecular landscape of recurrent cervical cancer
Cervical cancer (CC) is a major gynecological problem in developing and underdeveloped
countries. Despite the significant advancement in early detection and treatment modalities …
countries. Despite the significant advancement in early detection and treatment modalities …
Regulation and tumor‐suppressive function of the miR‐379/miR‐656 (C14MC) cluster in cervical cancer
Cervical cancer (CC) is a key contributor to cancer‐related mortality in several countries.
The identification of molecular markers and the underlying mechanism may help improve …
The identification of molecular markers and the underlying mechanism may help improve …
The progress of methylation regulation in gene expression of cervical cancer
C Feng, J Dong, W Chang, M Cui… - International journal of …, 2018 - Wiley Online Library
Cervical cancer is one of the most common gynecological tumors in females, which is
closely related to high‐rate HPV infection. Methylation alteration is a type of epigenetic …
closely related to high‐rate HPV infection. Methylation alteration is a type of epigenetic …
TC2N, a novel oncogene, accelerates tumor progression by suppressing p53 signaling pathway in lung cancer
X Hao, F Han, N Zhang, H Chen, X Jiang… - Cell Death & …, 2019 - nature.com
The protein containing the C2 domain has been well documented for its essential roles in
endocytosis, cellular metabolism and cancer. Tac2-N (TC2N) is a tandem C2 domain …
endocytosis, cellular metabolism and cancer. Tac2-N (TC2N) is a tandem C2 domain …
Biological implications and therapeutic significance of DNA methylation regulated genes in cervical cancer
Cervical cancer is the second most common cancer among women worldwide. About
528,000 women are diagnosed with cervical cancer contributing to around 266,000 deaths …
528,000 women are diagnosed with cervical cancer contributing to around 266,000 deaths …
DOC2B is a negative regulator of Wnt/β-catenin signaling pathway in cervical cancer
DOC2B is a ubiquitously expressed isoform of the double C-2 protein family that requires Ca
2+ for most of its physiological functions. Initial findings have indicated that DOC2B …
2+ for most of its physiological functions. Initial findings have indicated that DOC2B …
Double C-2 like domain beta (DOC2B) induces calcium dependent oxidative stress to promote lipotoxicity and mitochondrial dysfunction for its tumor suppressive …
Mitochondria are biosynthetic and bioenergetic organelles that regulate many biological
processes, including metabolism, oxidative stress, and cell death. Cervical cancer (CC) cells …
processes, including metabolism, oxidative stress, and cell death. Cervical cancer (CC) cells …
DNA methylation regulated microRNAs in human cervical cancer
Regulation of miRNA gene expression by DNA promoter methylation may represent a key
mechanism to drive cervical cancer progression. In order to understand the impact of DNA …
mechanism to drive cervical cancer progression. In order to understand the impact of DNA …