Intra-abdominal infections (IAIs) are common surgical emergencies and have been reported
as major contributors to non-trauma deaths in hospitals worldwide. The cornerstones of …

The high prevalence of cholesterol gallstones, the availability of new information about
pathogenesis, and the relevant health costs due to the management of cholelithiasis in both …

Background A reliable system for grading operative difficulty of laparoscopic
cholecystectomy would standardise description of findings and reporting of outcomes. The …

Background Laparoscopic cholecystectomy is increasingly performed in an ever ageing
population; however, the risks are poorly quantified. The study aims to review the current …

Biliary lithiasis is a global disorder affecting nearly 20% of the world's population, although
most cases occur without symptoms. Gallbladder stones could move into the common bile …

Background Acute cholecystitis is a life-threatening emergency in elderly patients. This
population-based cohort study aimed to evaluate the commonly used management …

Background Cholecystectomy on index admission for acute cholecystitis is associated with
improved patient outcomes. The timing of intervention is mainly driven by service provision …

Introduction: Cholesterol gallstone disease have relationships with various conditions linked
with insulin resistance, but also with heart disease, atherosclerosis, and cancer. These …

Background Evidence supports early laparoscopic cholecystectomy for acute cholecystitis.
Differences in treatment patterns between the USA and UK, associated outcomes and …

Introduction Cholecystectomy is a standard treatment in the management of symptomatic
gallstone disease. Current literature has contradicting views on the cost-effectiveness of …