Methods for controlling blood pharmacokinetics of antibodies
T Igawa, H Tsunoda, T Tachibana - US Patent 11,046,784, 2021 - Google Patents
The present inventors discovered that the half-life in blood of an IgG antibody which is a
polypeptide comprising an FcRn-binding domain can be controlled by controlling the …
polypeptide comprising an FcRn-binding domain can be controlled by controlling the …
Compositions and methods for increasing muscle mass and muscle strength by specifically antagonizing GDF8 and or Activin A
T Stitt, E Latres - US Patent 8,871,209, 2014 - Google Patents
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10/2002 Lee et al. 6,858,208 B2 2/2005 Lee et al. 7.241, 444 B2* 7/2007 Goetsch et …
Fc region variant
F Mimoto, H Katada, T Igawa - US Patent 11,267,868, 2022 - Google Patents
US11267868B2 - Fc region variant - Google Patents US11267868B2 - Fc region variant - Google
Patents Fc region variant Download PDF Info Publication number US11267868B2 …
Patents Fc region variant Download PDF Info Publication number US11267868B2 …
Compositions and methods for growth factor modulation
T Schurpf, NK Mahanthappa, MM Straub - US Patent 10,597,443, 2020 - Google Patents
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Compositions and methods for growth factor modulation
T Schurpf, NK Mahanthappa, MM Straub - US Patent 9,399,676, 2016 - Google Patents
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Compositions and methods for growth factor modulation
T Schurpf, NK Mahanthappa, MM Straub - US Patent 9,573,995, 2017 - Google Patents
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Antibodies that bind myostatin, compositions and methods
H Han, T Arora, Q Chen, HS Lu, X Zhou - US Patent 8,999,343, 2015 - Google Patents
US8999343B2 - Antibodies that bind myostatin, compositions and methods - Google Patents
US8999343B2 - Antibodies that bind myostatin, compositions and methods - Google Patents …
US8999343B2 - Antibodies that bind myostatin, compositions and methods - Google Patents …
Method of modifying isoelectric point of antibody via amino acid substitution in CDR
T Igawa, H Tsunoda, T Tachibana… - US Patent …, 2022 - Google Patents
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Antigen-binding molecule capable of binding two or more antigen molecules repeatedly
T Igawa, S Ishii, A Maeda, T Nakai - US Patent 10,472,623, 2019 - Google Patents
The present inventors discovered that antibodies having weaker antigen-binding activity at
the early endosomal pH in comparison with that at the pH of plasma are capable of binding …
the early endosomal pH in comparison with that at the pH of plasma are capable of binding …
FcgammaRIIB-specific Fc region variant
H Katada, S Kadono, F Mimoto, T Igawa - US Patent 10,919,953, 2021 - Google Patents
2015-04-23 Assigned to CHUGAI SEIYAKU KABUSHIKI KAISHA reassignment CHUGAI
SEIYAKU KABUSHIKI KAISHA ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
SEIYAKU KABUSHIKI KAISHA ASSIGNMENT OF ASSIGNORS INTEREST (SEE …