AC Finnefrock, TM Fu, DC Freed, DR Casimiro… - US Patent …, 2012 - Google Patents
The references cited throughout the present application are not admitted to be prior art to the claimed invention. Programmed Cell Death 1 (PD-1) is a 50-55 kDa type I transmembrane …
NJ Papadopoulos, AJ Murphy, G Thurston… - US Patent …, 2018 - Google Patents
The present invention provides antibodies that bind to the T-cell co-inhibitor programmed death-1 (PD-1) protein, and methods of use. In various embodiments of the invention, the …
S Langermann, L Liu, S Marshall, S Yao - US Patent 9,205,148, 2015 - Google Patents
The present invention relates to antibodies and their antigen-binding fragments and to other molecules that are capable of immunospecifically binding to B7-H1 or PD-1. In some …
AJ Korman, M Srinivasan, C Wang, MJ Selby… - US Patent …, 2014 - Google Patents
The present invention provides isolated monoclonal antibodies, particularly human monoclonal antibodies, that specifically bind to PD-1 with high affinity. Nucleic acid …
S Langermann, L Liu - US Patent 8,709,416, 2014 - Google Patents
5,175,099 A 12, 1992 Wills 5, 190,929 A 3, 1993 Borch(57) ABSTRACT-5,204.243 A 4, 1993 Paoletti Methods of treating cancer and infectious diseases utilizing a 5,223,409 A 6, 1993 …
AJ Korman, M Srinivasan, C Wang, MJ Selby… - US Patent …, 2016 - Google Patents
The present invention provides isolated monoclonal antibodies, particularly human monoclonal antibodies, that specifically bind to PD-1 with high affinity. Nucleic acid …
T Honjo, N Minato, Y Iwai, S Shibayama - US Patent 9,073,994, 2015 - Google Patents
Compositions for cancer or infection treatment via immuno potentiation caused by inhibition of immunosuppressive sig nal induced by PD-1, PD-L1, or PD-L2 and therapies using them …