We have tested the effect of metabolic inhibitors, membrane cholesterol depletion, and
detergent extraction of cell surface molecules on the susceptibility of MA104 cells to infection …

The recognition that rotaviruses are the major cause of life-threatening diarrheal disease
and significant morbidity in young children has focused efforts on disease prevention and …

Rotavirus A (RVA) genome segments can reassort upon co-infection of target cells with two
different RVA strains. However, not all reassortants are viable, which limits the ability to …

Annual deaths in infants and young children due to rotavirus (RV) infection are around
100,000 in India and about 600,000 globally. Development of a vaccine for this disease is a …

Rotavirus outer capsid proteins VP5*, VP8* and VP7 elicit neutralizing, protective
antibodies. The α2β1 integrin is a cellular receptor for rotavirus that is bound by VP5*. Some …

NSP4 and VP7 are important functional proteins of rotavirus. Proper combination of viral
gene expression is favorable to improving the protection effect of subunit vaccine. In the …

This report is of a community-based case control study to assess whether the severity of
acute diarrhea by rotavirus (RV) in young children is associated with a particular VP7 (G) or …

In the present investigation we characterized the antigenic diversity of the VP4 and VP7
proteins in 309 and 261 human rotavirus strains isolated during two consecutive epidemic …

Background In a study performed in 1983, 18 adult volunteers received oral challenge with
the virulent human rotavirus strain D (G1P1A [8], NSP4 [B]). To identify correlates of …

Oral delivery of specific IgY has been reported to be beneficial against rotavirus infection.
However, the production of IgYs against globally prevalent human rotavirus (HRV) serotypes …