Background Pulmonary hypertension (PH) is a life-threatening cardiopulmonary disorder
whose underlying pathogenesis is unknown. Our previous study showed that pulmonary …

Lipid-lowering agents are relevant in stroke prevention. Probucol (PU) is an antioxidative
and lipid-lowering drug that has been used to treat atherosclerotic cardiovascular diseases …

Background Pulmonary arterial hypertension (PAH) is a major concern in patients with
Down syndrome (DS) and congenital heart disease (CHD). Understanding the unique …

Excessive mitochondrial fission and a shift to a Warburg phenotype are hallmarks of
pulmonary hypertension (PH), although the mechanistic link between these processes …

Pyrrolizidine alkaloids (PAs) are a group of naturally occurring alkaloids widely present in
plants. PAs are highly hepatotoxic and have been documented to cause many incidents of …

Background Pulmonary hypertension (PH) is a complex multifactorial vascular pathology
characterized by an increased pulmonary arterial pressure, vasoconstriction, remodelling of …

Beetroot is a nitrate-rich vegetable with cardiovascular benefits. This study examined
whether ingestion of beetroot juice (BRJ) protects against pulmonary hypertension (PH) …

Antiplatelet, antihypertensive, and lipid-lowering agents are the three foundational agents
for secondary prevention of ischemic stroke, among which lipid-lowering is one of the most …

Background Pulmonary hypertension (PH) is a complex multifactorial vascular pathology
characterized by an increased pulmonary arterial pressure, vasoconstriction, remodelling of …

Dans la circulation pulmonaire, la mitochondrie contribue à la signalisation intracellulaire
physiologique via la production d'espèces réactives dérivées de l'oxygène (ERO) et joue …