[HTML][HTML] Mycotic keratitis—a global threat from the filamentous fungi

JJ Hoffman, MJ Burton, A Leck - Journal of Fungi, 2021 - mdpi.com
Mycotic or fungal keratitis (FK) is a sight-threatening disease, caused by infection of the
cornea by filamentous fungi or yeasts. In tropical, low and middle-income countries, it …

Photoactivated chromophore for infectious keratitis–Corneal cross-linking (PACK-CXL): A systematic review and meta-analysis

DSJ Ting, C Henein, DG Said, HS Dua - The Ocular Surface, 2019 - Elsevier
Purpose To examine the efficacy of adjuvant photoactivated chromophore for infectious
keratitis–corneal cross-linking (PACK-CXL) for the treatment of infectious keratitis (IK) …

Paradox of complex diversity: Challenges in the diagnosis and management of bacterial keratitis

RB Singh, S Das, J Chodosh, N Sharma… - Progress in Retinal and …, 2022 - Elsevier
Bacterial keratitis continues to be one of the leading causes of corneal blindness in the
developed as well as the developing world, despite swift progress since the dawn of the …

Management of filamentous fungal keratitis: a pragmatic approach

JJ Hoffman, S Arunga, AHA Mohamed Ahmed, VH Hu… - Journal of Fungi, 2022 - mdpi.com
Filamentous fungal infections of the cornea known as filamentous fungal keratitis (FK) are
challenging to treat. Topical natamycin 5% is usually first-line treatment following the results …

High fluence increases the antibacterial efficacy of PACK cross-linking

S Kling, FS Hufschmid, EA Torres-Netto… - Cornea, 2020 - journals.lww.com
Purpose: Photoactivated chromophore for keratitis cross-linking (PACK-CXL) is used as an
adjunct therapy to antibiotic medication in infectious keratitis. This experimental study aimed …

Evaluation of corneal cross-linking as adjuvant therapy for the management of fungal keratitis

A Wei, K Wang, Y Wang, L Gong, J Xu… - Graefe's Archive for Clinical …, 2019 - Springer
Purpose To evaluate the efficacy of corneal cross-linking (CXL) as adjuvant therapy for the
treatment of fungal ulcerative keratitis. Methods Forty-one patients with fungal ulcerative …

[HTML][HTML] Genipin in an ex vivo corneal model of bacterial and fungal keratitis

E Koudouna, M Huertas-Bello… - … Vision Science & …, 2021 - iovs.arvojournals.org
Purpose: To determine whether genipin (a natural crosslinker) could reduce the colonization
and proliferation of bacteria and fungi in an ex vivo model of corneal infection. Methods: This …

Urgent unmet needs in the care of bacterial keratitis: An evidence-based synthesis

L Ung, J Chodosh - The ocular surface, 2023 - Elsevier
Bacterial corneal infections, or bacterial keratitis (BK), are ophthalmic emergencies that
frequently lead to irreversible visual impairment. Though increasingly recognized as a major …

Does PACK-CXL change the prognosis of resistant infectious keratitis?

O Zloto, IS Barequet, A Weissman… - Journal of Refractive …, 2018 - journals.healio.com
PURPOSE: To examine the clinical characteristics, treatments, and prognosis of all cases of
infectious keratitis resistant to conventional therapy and treated by photo-activated …

Photoactivated chromophore corneal collagen cross-linking for infectious keratitis (PACK-CXL)—a comprehensive review of diagnostic and prognostic factors …

IR Barac, AR Artamonov, G Baltă, V Dinu… - Journal of Personalized …, 2022 - mdpi.com
Infectious keratitis is a severe infection of the eye, which requires urgent care in order to
prevent permanent complications. Typical cases are usually diagnosed clinically, whereas …