Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the Bleeding Academic Research Consortium

R Mehran, SV Rao, DL Bhatt, CM Gibson, A Caixeta… - Circulation, 2011 - Am Heart Assoc
Advances in antithrombotic therapy, along with an early invasive strategy, have reduced the
incidence of recurrent ischemic events and death in patients with acute coronary syndromes …

Combination antithrombotic therapies

PA Gurbel, US Tantry - Circulation, 2010 - Am Heart Assoc
or resistant” has been used to describe selected patients, especially high-risk patients and
diabetics, exhibiting high platelet function as measured by assays that are nonspecific in …

Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes (RIVAL): a randomised, parallel group, multicentre …

SS Jolly, S Yusuf, J Cairns, K Niemelä, D Xavier… - The Lancet, 2011 - thelancet.com
Background Small trials have suggested that radial access for percutaneous coronary
intervention (PCI) reduces vascular complications and bleeding compared with femoral …

Guidelines on myocardial revascularization: the task force on myocardial revascularization of the European Society of Cardiology (ESC) and the European …

Developed with the Special Contribution of … - European heart …, 2010 - academic.oup.com
Some surveys have shown that the intended users are sometimes unaware of the existence
of guidelines, or simply do not translate them into practice. Thus, implementation …

Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium

MB Leon, N Piazza, E Nikolsky, EH Blackstone… - Journal of the American …, 2011 - jacc.org
Objectives: To propose standardized consensus definitions for important clinical endpoints
in transcatheter aortic valve implantation (TAVI), investigations in an effort to improve the …

Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute …

SR Mehta, JF Tanguay, JW Eikelboom, SS Jolly… - The Lancet, 2010 - thelancet.com
Background Clopidogrel and aspirin are the most commonly used antiplatelet therapies for
percutaneous coronary intervention (PCI). We assessed the effect of various clopidogrel and …

[HTML][HTML] Dose comparisons of clopidogrel and aspirin in acute coronary syndromes

Current–Oasis 7 Investigators - New England Journal of Medicine, 2010 - Mass Medical Soc
Background Clopidogrel and aspirin are widely used for patients with acute coronary
syndromes and those undergoing percutaneous coronary intervention (PCI). However …

Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: a …

PG Steg, S James, RA Harrington, D Ardissino… - Circulation, 2010 - Am Heart Assoc
Background—Aspirin and clopidogrel are recommended for patients with acute coronary
syndromes (ACS) or undergoing coronary stenting. Ticagrelor, a reversible oral P2Y12 …

Effects of radial versus femoral artery access in patients with acute coronary syndromes with or without ST-segment elevation

SR Mehta, SS Jolly, J Cairns, K Niemela… - Journal of the American …, 2012 - jacc.org
Objectives: The purpose of this study was to determine the consistency of the effects of radial
artery access in patients with ST-segment elevation myocardial infarction (STEMI) and in …

Impaired bioavailability and antiplatelet effect of high-dose clopidogrel in patients after cardiopulmonary resuscitation (CPR)

L Součková, R Opatřilová, P Suk, I Čundrle… - European journal of …, 2013 - Springer
Purpose Bioavailability of clopidogrel in the form of crushed tablets administered via
nasogastric tube (NGT) has not been established in patients after cardiopulmonary …