Mechanistic insights into the impact of air pollution on pneumococcal pathogenesis and transmission

D Beentjes, RK Shears, N French, DR Neill… - American Journal of …, 2022 - atsjournals.org
Streptococcus pneumoniae (the pneumococcus) is the leading cause of pneumonia and
bacterial meningitis. A number of recent studies indicate an association between the …

Bacterial and viral respiratory tract microbiota and host characteristics in children with lower respiratory tract infections: a matched case-control study

WH Man, MA van Houten, ME Mérelle… - The Lancet …, 2019 - thelancet.com
Background Lower respiratory tract infections (LRTIs) are a leading cause of childhood
morbidity and mortality. Potentially pathogenic organisms are present in the respiratory tract …

Pneumococcal vaccines: host interactions, population dynamics, and design principles

NJ Croucher, A Løchen… - Annual review of …, 2018 - annualreviews.org
Streptococcus pneumoniae (the pneumococcus) is a nasopharyngeal commensal and
respiratory pathogen. Most isolates express a capsule, the species-wide diversity of which …

The nasopharyngeal microbiota in patients with viral respiratory tract infections is enriched in bacterial pathogens

S Edouard, M Million, D Bachar, G Dubourg… - European Journal of …, 2018 - Springer
The nasopharynx is the primary site of colonization by respiratory pathogen that constitutes
the port of entrance in the respiratory tract. The role of mucosal respiratory microbiota in …

Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine

WAA de Steenhuijsen Piters, SP Jochems… - Nature …, 2019 - nature.com
Streptococcus pneumoniae is the main bacterial pathogen involved in pneumonia.
Pneumococcal acquisition and colonization density is probably affected by viral co …

Dolosigranulum pigrum cooperation and competition in human nasal microbiota

SD Brugger, SM Eslami, MM Pettigrew, IF Escapa… - Msphere, 2020 - Am Soc Microbiol
Multiple epidemiological studies identify Dolosigranulum pigrum as a candidate beneficial
bacterium based on its positive association with health, including negative associations with …

Oral microbiome shifts from caries-free to caries-affected status in 3-year-old Chinese children: a longitudinal study

H Xu, J Tian, W Hao, Q Zhang, Q Zhou, W Shi… - Frontiers in …, 2018 - frontiersin.org
As one of the most prevalent human infectious diseases, dental caries results from dysbiosis
of the oral microbiota driven by multiple factors. However, most of caries studies were cross …

[HTML][HTML] Composition and comparison of the ocular surface microbiome in infants and older children

KM Cavuoto, S Banerjee, D Miller… - … vision science & …, 2018 - jov.arvojournals.org
Purpose: Unlike other microbiomes of the body, the composition of the ocular surface
microbiome (OSM) in children has yet to be thoroughly explored. Our goal was to evaluate …

Nasopharyngeal Codetection of Haemophilus influenzae and Streptococcus pneumoniae Shapes Respiratory Syncytial Virus Disease Outcomes in Children

A Diaz-Diaz, E Bunsow… - The Journal of …, 2022 - academic.oup.com
Background The role of nasopharyngeal bacteria in respiratory syncytial virus (RSV)
disease has been underestimated. We measured the frequency and burden of respiratory …

Differential nasopharyngeal microbiota composition in children according to respiratory health status

D Henares, P Brotons, MF De Sevilla… - Microbial …, 2021 - microbiologyresearch.org
Acute respiratory infections (ARIs) constitute one of the leading causes of antibiotic
administration, hospitalization and death among children< 5 years old. The upper …