Acetaminophen induced hepatotoxicity: An overview of the promising protective effects of natural products and herbal formulations

S Chilvery, A Yelne, A Khurana, MA Saifi, S Bansod… - Phytomedicine, 2023 - Elsevier
Background The liver plays an important role in regulating the metabolic processes and is
the most frequently targeted organ by toxic chemicals. Acetaminophen (APAP) is a well …

A review of biological and pharmacological activities of Baccharis trimera

ACS Rabelo, DC Costa - Chemico-Biological Interactions, 2018 - Elsevier
Plant-based systems continue to play an essential role in healthcare, and their use by
different cultures has been extensively documented. Baccharis trimera, popularly known as …

Hepatoprotective native plants documented in Brazilian traditional medicine literature: Current knowledge and prospects

C Antunes, MD Arbo, EL Konrath - Chemistry & Biodiversity, 2022 - Wiley Online Library
The native flora of Brazil covers a large biodiversity of plants, some of which have important
pharmacological properties. Ethnobotanical studies have established that the folk use of …

Promising therapeutic use of Baccharis trimera (Less.) DC. as a natural hepatoprotective agent against hepatic lesions that are caused by multiple risk factors

RJ Barbosa, GR da Silva, IM Cola, JC Kuchler… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Baccharis trimera (Less.) DC is a perennial
subshrub, popularly known as “carqueja,” that belongs to the Asteraceae family …

Use of medicinal plants with teratogenic and abortive effects by pregnant women in a city in Northeastern Brazil

CRF de Araújo, FG Santiago, MI Peixoto… - Revista Brasileira de …, 2016 - thieme-connect.com
Purpose The purpose of this study is to verify the use of medicinal plants by pregnant
women treated at four Basic Health Units and at a public maternity facility in Brazil's …

Baccharis trimera protects against ethanol induced hepatotoxicity in vitro and in vivo

ACS Rabelo, K de Pádua Lúcio, CM Araújo… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance Baccharis trimera has been traditionally used in Brazil to
treat liver diseases. Aim of the study To evaluate the protective effect of Baccharis trimera in …

Hydroethanolic extract of Baccharis trimera ameliorates alcoholic fatty liver disease in mice

FA dos Reis Livero, GG Martins, JEQ Telles… - Chemico-Biological …, 2016 - Elsevier
Ethanol abuse is a serious public health problem that is associated with several stages of
alcoholic liver disease (ALD) and a high incidence of morbidity and mortality. Alcoholic fatty …

Lycopene inhibits reactive oxygen species production in SK-Hep-1 cells and attenuates acetaminophen-induced liver injury in C57BL/6 mice

ACB Bandeira, TP da Silva, GR de Araujo… - Chemico-Biological …, 2017 - Elsevier
Our aim was to investigate the antioxidant potential of lycopene in different experimental
liver models: in vitro, to evaluate the influence of lycopene on reactive oxygen species …

Hepato- and cardioprotective effects of Baccharis trimera (Less.) DC. against multiple risk factors for chronic noncommunicable diseases

TC Mendes, GRDA Silva, AO Silva… - Anais da Academia …, 2021 - SciELO Brasil
Cardiovascular diseases are associated with high morbidity and mortality worldwide and
have several risk factors, including dyslipidemia, smoking, and hypertension. Studies have …

Baccharis trimera Infusion Reduces Macrophages Activation and High-Fat Diet-Induced Metabolic Disorders in Mice

TVN Ximenes, R Carvalho, IS Bonfá, VS Santos… - Pharmaceuticals, 2022 - mdpi.com
The aim of this study is to evaluate the efficacy of Baccharis trimera infusion on high-fat diet-
induced metabolic disorders in mice and macrophages activation. This study evaluated …