Every year in the United States, an estimated 500,000 babies are born preterm (before 37
completed weeks of gestation), and this number is rising, along with the recognition of brain …

In this review, we propose a broader view of the role of the fibroblast growth factor (FGF)
family in modulating brain function. We suggest that some of the FGF ligands together with …

Perineuronal nets (PNNs), a specialized form of extracellular matrix, are abnormal in the
brains of people with Rett syndrome (RTT). We previously reported that PNNs function to …

The mechanisms regulating hippocampal neurogenesis remain poorly understood.
Particularly unclear is the extent to which age-related declines in hippocampal …

Objective: Vascular dementia (VaD) is the second most common cause of dementia
worldwide. The increasing contribution of lifestyle-associated risk factors to VaD has pointed …

Some individuals are able to maintain their cognitive abilities despite the presence of
significant Alzheimer's Disease (AD) neuropathological changes. This discrepancy between …

Endocrine fibroblast growth factor 23 (FGF23) is predominantly secreted by osteocytes and
facilitates renal phosphate excretion. However, FGF23 is also present in cerebrospinal fluid …

Infants born premature experience hypoxic episodes due to immaturity of their respiratory
and central nervous systems. This profoundly affects brain development and results in …

Background Despite strong evidence linking fibroblast growth factor 2 (FGF2) with anxiety
and depression in both rodents and humans, the molecular mechanisms linking FGF2 with …

The number of people diagnosed with Alzheimer's disease (AD) is increasing steadily as the
world population ages, thus creating a huge socio-economic burden. Current treatments …