Executive summary Although health outcomes have improved in low-income and middle-
income countries (LMICs) in the past several decades, a new reality is at hand. Changing …

Executive summary Tuberculosis can be treated, prevented, and cured. Rapid, sustained
declines in tuberculosis deaths in many countries during the past 50 years provide …

Background While tuberculosis incidence and mortality are declining in South Africa,
meeting the goals of the End TB Strategy requires an invigorated programmatic response …

Drug-resistant tuberculosis is a major public health concern in many countries. Over the past
decade, the number of patients infected with Mycobacterium tuberculosis resistant to the …

The cascade of care is a model for evaluating patient retention across sequential stages of
care required to achieve a successful treatment outcome. This approach was first used to …

Despite the high coverage of directly observed treatment short-course (DOTS), tuberculosis
(TB) continues to affect 10.4 million people each year, and kills 1.8 million. High TB mortality …

Rapid, accurate, sputum-free tests for tuberculosis (TB) triage and confirmation are urgently
needed to close the widening diagnostic gap. We summarise key technologies and review …

Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-
attributable deaths worldwide and is driven by both ongoing resistance acquisition and …

Tuberculosis diagnosis and treatment currently revolves around clinical features and
microbiology. The disease however adversely affects patients' psychological, economic, and …

Background India has the highest burden of tuberculosis (TB). Although most patients with
TB in India seek care from the private sector, there is limited evidence on quality of TB care …