▪ Abstract Src family protein tyrosine kinases are activated following engagement of many
different classes of cellular receptors and participate in signaling pathways that control a …

Tendon injuries are common and debilitating, with non-regenerative healing often resulting
in chronic disease. While there has been considerable progress in identifying the cellular …

Although eosinophils are considered useful in defense mechanisms against parasites, their
exact function in innate immunity remains unclear. The aim of this study is to better …

This best-selling resource has a worldwide reputation as the leader in its field. Focusing on
human immunology and biology, while also reporting on scientific experimentation and …

Blood eosinophilia and tissue eosinophilia are characteristic features of allergic
inflammation and asthma, conditions associated with prominent production of TH2 cytokines …

The cytoplasmic protein tyrosine kinase Syk has two amino-terminal SH2 domains that
engage phosphorylated immunoreceptor tyrosine-based activation motifs in the signaling …

Nasal polyps, which often occur in association with allergic rhinitis and asthma, are
characterized by a marked infiltration of eosinophils. Using a method for detecting …

IL-3, IL-5, and GM-CSF are related hematopoietic cytoines that are important for allergic
inflammation. The receptors for human IL-5, IL-3, and GM-CSF are members of the …

Neutrophils are constantly produced in large numbers in the bone marrow, and the same
numbers of cells need to die within a defined time period in order to keep cellular …

The role of cytokines in the accumulation of eosinophil granulocytes in inflamed tissue has
been studied extensively during recent years, and these molecules have been found to …