[HTML][HTML] The GABA excitatory/inhibitory developmental sequence: a personal journey

Y Ben-Ari - Neuroscience, 2014 - Elsevier
The developing brain is talkative but its language is not that of the adult. Most if not all
voltage and transmitter-gated ionic currents follow a developmental sequence and network …

The neuropathology of autism

MF Casanova - The molecular basis of autism, 2015 - Springer
Most researchers agree that autism spectrum disorders (ASD) comprise a group of
developmental conditions whose pathological substratum resides in the brain. Despite the …

Elevated fetal steroidogenic activity in autism

S Baron-Cohen, B Auyeung… - Molecular …, 2015 - nature.com
Autism affects males more than females, giving rise to the idea that the influence of steroid
hormones on early fetal brain development may be one important early biological risk factor …

The neurobiology of autism spectrum disorders

M Parellada, MJ Penzol, L Pina, C Moreno… - European …, 2014 - cambridge.org
Data is progressively and robustly accumulating regarding the biological basis of autism.
Autism spectrum disorders (ASD) are currently considered a group of neurodevelopmental …

Defining precision medicine approaches to autism spectrum disorders: concepts and challenges

E Loth, DG Murphy, W Spooren - Frontiers in psychiatry, 2016 - frontiersin.org
The tremendous clinical and etiological variability between individuals with autism spectrum
disorder (ASD) has made precision medicine the most promising treatment approach. It aims …

General developmental health in the VPA-rat model of autism

MR Favre, TR Barkat, D LaMendola… - Frontiers in behavioral …, 2013 - frontiersin.org
Autism is a neurodevelopmental condition diagnosed by impaired social interaction,
abnormal communication and, stereotyped behaviors. While post-mortem and imaging …

Is birth a critical period in the pathogenesis of autism spectrum disorders?

Y Ben-Ari - Nature Reviews Neuroscience, 2015 - nature.com
Birth is associated with a neuroprotective, oxytocin-mediated abrupt excitatory-to-inhibitory
GABA shift that is abolished in autism, and its restoration attenuates the disorder in offspring …

[HTML][HTML] mTOR signalling pathway-A root cause for idiopathic autism?

H Ganesan, V Balasubramanian, M Iyer… - BMB …, 2019 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is a complex neurodevelopmental monogenic disorder with
a strong genetic influence. Idiopathic autism could be defined as a type of autism that does …

Autism spectrum disorders: the quest for genetic syndromes

DI Zafeiriou, A Ververi, V Dafoulis… - American Journal of …, 2013 - Wiley Online Library
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disabilities with various etiologies, but with a heritability estimate of more than 90 …

Impairments in dendrite morphogenesis as etiology for neurodevelopmental disorders and implications for therapeutic treatments

T Copf - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Dendrite morphology is pivotal for neural circuitry functioning. While the causative
relationship between small-scale dendrite morphological abnormalities (shape, density of …