The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …

Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …

Dynamin is a GTPase protein that is essential for membrane fission during clathrin-mediated
endocytosis in eukaryotic cells. Dynasore is a GTPase inhibitor that rapidly and reversibly …

▪ Abstract Lipid raft microdomains were conceived as part of a mechanism for the
intracellular trafficking of lipids and lipid-anchored proteins. The raft hypothesis is based on …

Virus-like particles (VLPs) are formed by the self-assembly of envelope and/or capsid
proteins from many viruses. In many cases such VLPs have structural characteristics and …

Zaire ebolavirus (ZEBOV), a highly pathogenic zoonotic virus, poses serious public health,
ecological and potential bioterrorism threats. Currently no specific therapy or vaccine is …

Ebolavirus (EBOV) is an enveloped, single-stranded, negative-sense RNA virus that causes
severe hemorrhagic fever with mortality rates of up to 90% in humans and nonhuman …

Increasing evidence suggests that biological membranes can be laterally subdivided into
domains enriched in specific lipid and protein components and that these domains may be …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first discovered in
December 2019 in Wuhan, China, and expeditiously spread across the globe causing a …

As intracellular parasites, viruses rely heavily on the use of numerous cellular machineries
for completion of their replication cycle. The recent discovery of the heterogeneous …