Osteoimmunity is involved in regulating the balance of bone remodeling and resorption, and
is essential for maintaining normal bone morphology. The interaction between immune cells …

MicroRNAs (miRNAs) are crucial post-transcriptional regulators of haematopoietic cell fate
decisions. They act by negatively regulating the expression of key immune development …

Exosomes, also known as extracellular vesicles, are naturally occurring, biocompatible, and
bioacive nanoparticles ranging from 40 to 150 nm in diameter. Bone-secreted exosomes …

Macrophages are myeloid immune cells that are strategically positioned throughout the
body tissues, where they ingest and degrade dead cells, debris, and foreign material and …

The innate inflammatory response must be tightly regulated to ensure effective immune
protection. NF-κB is a key mediator of the inflammatory response, and its dysregulation has …

Antisense techniques have been employed for over 30 years to suppress expression of
target RNAs. Recently, microRNAs (miRNAs) have emerged as a new class of small, non …

MicroRNAs (miRNAs) repress cellular protein levels to provide a sophisticated parameter of
gene regulation that coordinates a broad spectrum of biological processes. Bone …

microRNA is necessary for osteoclast differentiation, function and survival. It has been
reported that miR-199/214 cluster plays important roles in vertebrate skeletal development …

Understanding the mechanism by which tumor cells influence osteoclast differentiation is
crucial for improving treatment of osteolytic metastasis. Here, we report broad microRNA …

MicroRNAs (miRNAs) posttranscriptionally regulate gene expression by repressing protein
synthesis and exert a broad influence over development, physiology, adaptation, and …