Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

Staphylococcus aureus is a member of the human commensal microflora that exists,
apparently benignly, at multiple sites on the host. However, as an opportunist pathogen it …

The heme peroxidase family generates a battery of oxidants both for synthetic purposes, and
in the innate immune defence against pathogens. Myeloperoxidase (MPO) is the most …

The surveillance and elimination of fungal pathogens rely heavily on the sentinel behaviour
of phagocytic cells of the innate immune system, especially macrophages and neutrophils …

Talaromycosis is an invasive mycosis endemic in tropical and subtropical Asia and is
caused by the pathogenic fungus Talaromyces marneffei. Approximately 17,300 cases of T …

The immune response to Candida species is shaped by the commensal character of the
fungus. There is a crucial role for discerning between colonization and invasion at mucosal …

Reactive oxygen species (ROS) can attack a diverse range of targets to exert antimicrobial
activity, which accounts for their versatility in mediating host defense against a broad range …

Review of myeloperoxidase supporting optimal microbicidal activity in the phagosomes of
human neutrophils. Successful immune defense requires integration of multiple effector …

The heme protein myeloperoxidase (MPO) is a major constituent of neutrophils. As a key
mediator of the innate immune system, neutrophils are rapidly recruited to inflammatory …