Recent developments in the chemical biology of amyloid-β oligomer targeting

Y Wang, J Chen, F Gao, M Hu, X Wang - Organic & Biomolecular …, 2023 - pubs.rsc.org
Aggregation of amyloid-β (Aβ) peptides is characteristic of Alzheimer's disease (AD), which
is the most common neurodegenerative disorder. Increasing evidence shows that Aβ …

Mitigation of indoor pollutants using 2D materials for enrichment of indoor environmental quality and human health: a review

M Subramani, A Muralidharan, D Arumugam… - Current Opinion in …, 2023 - Elsevier
Indoor pollution includes particulate matter (PM), volatile organic compounds (VOCs),
volatile inorganic compounds (VICs), and pathogens that pose a potential risk to human …

Insights into the interaction between the kusaginin and bovine serum albumin: multi‐spectroscopic techniques and computational approaches

F Huang, C Chen - Journal of Molecular Recognition, 2023 - Wiley Online Library
Kusaginin, as a phenylethanoid glycoside, which has exhibited wide antioxidant and
antimicrobial properties. The molecular mechanism underlying the broad biological activities …

Structural exploration of interactions of (+) catechin and (−) epicatechin with bovine serum albumin: Insights from molecular dynamics and spectroscopic methods

S Anitha, V Saranya, R Shankar, V Sasirekha - Journal of Molecular Liquids, 2022 - Elsevier
The interaction of two stereoisomeric flavanols (+) catechin (CT) and (−) epicatechin (ECT)
with bovine serum albumin (BSA) has been studied using UV–Vis absorption and …

Evidence of cadmium and mercury involvement in the Aβ42 aggregation process

D Meleleo, C Sblano, MM Storelli, R Mallamaci - Biophysical Chemistry, 2020 - Elsevier
Aβ42 is a small peptide formed from 42 aminoacids that presents a great propensity to
aggregate until it forms fibrils. Aβ42 aggregation and fibrillation are very complex processes …

The nickel-chelator dimethylglyoxime inhibits human amyloid beta peptide in vitro aggregation

SL Benoit, RJ Maier - Scientific Reports, 2021 - nature.com
One of the hallmarks of the most common neurodegenerative disease, Alzheimer's disease
(AD), is the extracellular deposition and aggregation of Amyloid Beta (Aβ)-peptides in the …

Mechanistic Insights of TiO2 Nanoparticles with Different Surface Charges on Aβ42 Peptide Early Aggregation: An In Vitro and In Silico Study

Q Li, J Wen, Z Yan, H Sun, E Song, Y Song - Langmuir, 2023 - ACS Publications
Humans may intendedly or unintendedly be exposed to nanomaterials through food, water,
and air. Upon exposure, nanomaterials can pierce the bloodstream and translocate to …

Effect of tert-alcohol functional imidazolium salts on oligomerization and fibrillization of amyloid β (1–42) peptide

MS Said, GR Navale, A Yadav, N Khonde… - Biophysical …, 2020 - Elsevier
Imidazolium based IL's has gained vast interest in developing biological applications.
Oligomerization and fibrillization of amyloid β (1–42) peptide are mainly responsible for the …

The impact of halogenated phenylalanine derivatives on NFGAIL amyloid formation

S Chowdhary, J Moschner, DJ Mikolajczak… - …, 2020 - Wiley Online Library
Abstract The hexapeptide hIAPP22–27 (NFGAIL) is known as a crucial amyloid core
sequence of the human islet amyloid polypeptide (hIAPP) whose aggregates can be used to …

An update in toxicology of ageing

L Rackova, M Mach, Z Brnoliakova - Environmental Toxicology and …, 2021 - Elsevier
The field of ageing research has been rapidly advancing in recent decades and it had
provided insight into the complexity of ageing phenomenon. However, as the organism …