Evolutionary analysis of a complete chicken genome

Z Huang, Z Xu, H Bai, Y Huang… - Proceedings of the …, 2023 - National Acad Sciences
Microchromosomes are prevalent in nonmammalian vertebrates [PD Waters et al., Proc.
Natl. Acad. Sci. USA 118 (2021)], but a few of them are missing in bird genome assemblies …

Genomic and epigenetic foundations of neocentromere formation

EM DeBose-Scarlett, BA Sullivan - Annual review of genetics, 2021 - annualreviews.org
Centromeres are essential to genome inheritance, serving as the site of kinetochore
assembly and coordinating chromosome segregation during cell division. Abnormal …

Kinetochore assembly throughout the cell cycle

AP Navarro, IM Cheeseman - Seminars in cell & developmental biology, 2021 - Elsevier
The kinetochore plays an essential role in facilitating chromosome segregation during cell
division. This massive protein complex assembles onto the centromere of chromosomes and …

Centromere/kinetochore is assembled through CENP-C oligomerization

M Hara, M Ariyoshi, T Sano, RS Nozawa, S Shinkai… - Molecular cell, 2023 - cell.com
Kinetochore is an essential protein complex required for accurate chromosome segregation.
The constitutive centromere-associated network (CCAN), a subcomplex of the kinetochore …

Human centromere repositioning activates transcription and opens chromatin fibre structure

C Naughton, C Huidobro, CR Catacchio… - Nature …, 2022 - nature.com
Human centromeres appear as constrictions on mitotic chromosomes and form a platform for
kinetochore assembly in mitosis. Biophysical experiments led to a suggestion that repetitive …

Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin

C Sacristan, K Samejima, LA Ruiz, M Deb… - Cell, 2024 - cell.com
Centromeres are scaffolds for the assembly of kinetochores that ensure chromosome
segregation during cell division. How vertebrate centromeres obtain a three-dimensional …

Birth, evolution, and transmission of satellite-free mammalian centromeric domains

SG Nergadze, FM Piras, R Gamba, M Corbo… - Genome …, 2018 - genome.cshlp.org
Mammalian centromeres are associated with highly repetitive DNA (satellite DNA), which
has so far hindered molecular analysis of this chromatin domain. Centromeres are …

Critical foundation of the kinetochore: the constitutive centromere-associated network (CCAN)

M Hara, T Fukagawa - Centromeres and Kinetochores: Discovering the …, 2017 - Springer
The kinetochore is a large protein complex, which is assembled at the centromere of a
chromosome to ensure faithful chromosome segregation during M-phase. The centromere in …

Centromere identity and the regulation of chromosome segregation

K Sundararajan, AF Straight - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Eukaryotes segregate their chromosomes during mitosis and meiosis by attaching
chromosomes to the microtubules of the spindle so that they can be distributed into daughter …

A genetic memory initiates the epigenetic loop necessary to preserve centromere position

S Hoffmann, HM Izquierdo, R Gamba, F Chardon… - The EMBO …, 2020 - embopress.org
Centromeres are built on repetitive DNA sequences (CenDNA) and a specific chromatin
enriched with the histone H3 variant CENP‐A, the epigenetic mark that identifies centromere …