Vesicular stomatitis virus (VSV), a negative-strand RNA virus of the Vesiculovirus genus, has
demonstrated encouraging anti-neoplastic activity across multiple human cancer types. VSV …

Inhalation of Yersinia pestis bacilli causes pneumonic plague, a rapidly progressing and
exceptionally virulent disease. Extensively antibiotic-resistant Y. pestis strains exist and we …

The earliest known route of vaccination was respiratory, by intranasal insufflation of
powdered scab material containing variola virus from smallpox patients, reportedly practiced …

Abstract Background Nipah virus (NiV), a zoonotic pathogen causing severe respiratory
illness and encephalitis in humans, emerged in Malaysia in 1998 with subsequent …

Yersinia pestis is one of the world's most virulent human pathogens. Inhalation of this Gram‐
negative bacterium causes pneumonic plague, a rapidly progressing and usually fatal …

Plague is one of the world's most lethal human diseases caused by Yersinia pestis, a Gram-
negative bacterium. Despite overwhelming studies for many years worldwide, there is no …

Appropriate choice of vaccine vector is crucial for effective vaccine development.
Rhabdoviral vectors, such as rabies virus and vesicular stomatitis virus, have been used in a …

Nipah virus (NiV) continues to cause outbreaks of fatal human encephalitis due to spillover
from its bat reservoir. We determined that a single dose of replication-defective vesicular …

An overview is given on the development of technologies to allow reverse genetics of RNA
viruses, ie, the rescue of viruses from cDNA, with emphasis on nonsegmented negative …

The potential application of Yersinia pestis for bioterrorism emphasizes the urgent need to
develop more effective vaccines against airborne infection. The current status of plague …