Ever since its discovery by Windhaus, the importance of the active metabolite of vitamin D (1,
25-dihydroxyvitamin D 3; 1, 25-(OH) 2D 3) has been ever expanding. In this review, the …

Abstract Introduction In Europe, vitamin D deficiency is highly prevalent varying between
40% and 60% in the healthy general adult population. The consequences of vitamin D …

The Nrf2-Keap1-ARE pathway is the principal regulator of antioxidant and phase II
detoxification genes. Its activation increases the expression of antioxidant and cytoprotective …

Background There is a high prevalence of vitamin D deficiency in the critically ill patient
population. Several intensive care unit studies have demonstrated an association between …

Retrospective studies showed a relationship between vitamin D status and COVID-19
severity and mortality, with an inverse relation between SARS-CoV-2 positivity and …

Vitamin D is well known for its classic role in the maintenance of bone mineral density.
However, vitamin D also has an important “non-classic” influence on the body's immune …

Sepsis is characterized by characterized by early massive catabolism, lean body mass
(LBM) loss and escalating hypermetabolism persisting for months to years. Early enteral …

Sarcopenia occurring as a primary consequence of aging and secondary due to certain
medical problems including chronic disease, malnutrition and inactivity is a progressive …

Introduction Vitamin D plays a key role in immune function. Deficiency may aggravate the
incidence and outcome of infectious complications in critically ill patients. We aimed to …

Purpose Low vitamin D blood levels are associated with high mortality in critically ill patients.
There is controversy about vitamin D supplementation in this population. The objective of …