The nucleus of a cardiomyocyte has been increasingly recognized as a morphologically
distinct and partially independent calcium (Ca2+) signaling microdomain, with its own Ca2+ …

The release of peptide hormones is predominantly regulated by a transient increase in
cytosolic Ca2+ concentration ([Ca2+] c). To trigger exocytosis, Ca2+ ions enter the cytosol …

Organotypic culture of human ventricular myocardium is emerging in basic and translational
cardiac research. However, few institutions have access to human ventricular tissue …

Although natural dual‐ion exchangers are indispensable for bio‐organic functions,
developing their artificial counterparts remains nearly unexplored. Herein, this work …

Alcohol use disorder (AUD) is characterized by loss of intake control, increased anxiety, and
susceptibility to relapse inducing stressors. Both astrocytes and neurons contribute to …

Abstract Ethnopharmacological relevance The genus Pteris (Pteridaceae) has been used as
a traditional herb for a long time. In particular, Pteris laeta Wall. ex Ettingsh. has been widely …

Neuropathic pain is caused by injury or disease of the somatosensory system, and its course
is usually chronic. Several studies have been dedicated to investigating neuropathic pain …

New psychoactive substances (NPS) are an issue of global concern posing a serious threat
to the healthcare systems. Consumption of some NPS has been associated with toxic effects …

Autophagy phenomenon in the cell maintains proteostasis balance by eliminating damaged
organelles and protein aggregates. Imbalance in autophagic flux may cause accumulation …

Objectives Dental pain, which is the main reason for patients consulting dentists, is classified
as a public health concern. The study of cellular and molecular mechanisms contributing to …