It is well known that tumours arising in different organs are innervated and that 'perineural
invasion'(cancer cells escaping from the tumour by following the nerve trunk) is a negative …

Background Many drugs approved for other indications can control the growth of tumor cells
and limit adverse events (AE). Data sources Literature searches with keywords 'repurposing …

Background Beta-blocker (BB) is suggested to have anticancer efficacy. However, the
potential influence of BB use on overall survival (OS) in patients with lung cancer remains …

Despite advances in cancer treatment, current cancer incidence and prevalence still
demand multimodal treatments to enhance survival and clinical outcomes. Drugs used in …

The lungs are a key organ in the respiratory system. They are regulated by a complex
network of nerves that control their development, structure, function, and response to various …

Introduction: Beta-blockers (BB) are commonly used to manage cardiovascular disease and
may have benefits in controlling complications of anti-HER2 therapies. This study aimed to …

Arterial hypertension is one of the most frequent comorbidities in patients with cancer.
Studies have indicated that drugs used to control hypertension may alter cancer patient …

We support the notion that the neural connections of the tumor microenvironment (TME) and
the associated 'bioelectricity'play significant role in the pathophysiology of cancer. In several …

Hypertension is the prevailing independent risk factor for cardiovascular disease worldwide.
Anti-hypertensive drugs are the common and effective cure for lowering blood pressure in …

The mechanisms stimulating tumor progression are distinct from those responsible for
initiation. This fact may underlie the fact that while the relationship between stress and tumor …