Arginine (Arg) is a natural amino acid with an acceptable safety profile and a unique
chemical structure. Arg and its salts are highly effective in enhancing protein refolding and …

Ionic liquids (ILs) are environment-friendly solvents with potential applications in
biochemical reactions and as pharmaceutical ingredients. They are used to stabilize …

Osmolytes are known to stabilize proteins under stress conditions. Thermal denaturation
studies on globular proteins (β-lactoglobulin, cytochrome c, myoglobin, α-chymotrypsin) in …

This study evaluated the effect of glutamate supplementation on the physiological
parameters of heat-stressed Hu sheep. Forty-eight male Hu sheep with an average initial …

Lactoferrin (Lf) is an iron-binding glycoprotein and a component of many external secretions
with a wide diversity of functions. Structural studies are important to understand the …

Osmolytes alter the stability and aggregation of proteins. The effect of mixture of osmolytes is
generally not a simple additive of their individual effects. Here, we examine the effect of …

In the present study, we investigate the interaction of amino acid osmolytes, Arg, Lys, Asp
and Glu, and a denaturant, guanidinium chloride (Gdm) with proteins. To achieve this …

Studies on osmolyte-induced effects on proteins help in enhancing protein stability under
stressed conditions for various applications. Using mixtures of osmolytes could indeed …

Abstract The essential SecA motor ATPase acts in concert with the SecYEG translocon to
secrete proteins into the periplasmic space of Escherichia coli. In aqueous solutions, SecA …

Much is known about the structure, function, and stability of the SecA motor ATPase that
powers the secretion of periplasmic proteins across the inner membrane of Escherichia coli …